Results 171 to 180 of about 83,252 (267)

Allosteric DNAzyme‐Enabled Sensitive and Multiplex Detection of Biomarkers for Rapid Diagnosis of Urinary Tract Infections

Advanced Science, EarlyView.
A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen, Chenzhi Shi, Xiaowei Ma, Pengfei Hou, Haomin Zhang, Juanxiu Qin, Li Pan, Guilin Li, Lifei Gao, Qian Ma, Donglei Yang, Min Li, Pengfei Wang   +12 more
wiley   +1 more source

Cell-Based Immuno-Biosensors Using Microfluidics. [PDF]

Sensors (Basel)
Pugner B, Petersson E, Ahmed S, Mustafa M, Okoh J, Qiang Y.   +5 more
europepmc   +1 more source

A Dual‐Channel Synergistic Ultrasensitive Biosensor for Tumor Liquid Biopsy

Advanced Science, EarlyView.
ABSTRACT Liquid biopsy technology, which detects circulating tumor DNA (ctDNA) in cerebrospinal fluid, plays a crucial role in the early diagnosis and precision treatment of gliomas. However, the intrinsically low abundance and rapid clearance of ctDNA pose substantial challenges for conventional analytical techniques, such as droplet digital PCR and ...
Yu Sun, Jing Zhang, Chenqing Liu, Jing Lou, Sihui Wang, Xiangtian Ji, Xiaofang Zhao, Shirui Xu, Jingyu Feng, Bin Liu, Chao Chang, Qinggang Ge, Jun Yang   +12 more
wiley   +1 more source

Electrochemical Lateral Flow Platforms: Pioneering the Future of Rapid Testing. [PDF]

Molecules
Carvalho JPRS, Prado IC, Rangel K, Waterman JA, De-Simone SG.   +4 more
europepmc   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

High-Precision Detection of Magnetic Nanoparticles in Microfluidic Biosensing Systems. [PDF]

Biosensors (Basel)
Brown D, Manuel W, Luu D, Luong TD, Vega MM, Phan MH.   +5 more
europepmc   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Precision oncology at the nanoscale: nano-optical biosensors for early cancer detection. [PDF]

RSC Adv
Hassan YM, El-Tantawi H, Ali IR, Attia MS.   +3 more
europepmc   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Progress in Machine Learning-Assisted Biosensors for Alzheimer's Disease. [PDF]

Biosensors (Basel)
Feng Y, Chen C.
europepmc   +1 more source