Results 71 to 80 of about 11,414 (233)

Unveiling microbial preservation under hyperacidic and oxidizing conditions in the Oligocene Rio Tinto deposit

open access: yesScientific Reports, 2021
The preservation of biosignatures on Mars is largely associated with extensive deposits of clays formed under mild early Noachian conditions (> 3.9 Ga). They were followed by widespread precipitation of acidic sulfates considered adverse for biomolecule ...
David C. Fernández-Remolar   +8 more
doaj   +1 more source

Prebiotic Organic Microstructures [PDF]

open access: yes, 2011
Micro- and sub-micrometer spheres, tubules and fiber-filament soft structures have been synthesized in our experiments conducted with 3 MeV proton irradiations of a mixture of simple inorganic constituents, CO, N2 and H2O.
A Yoshihara   +26 more
core   +2 more sources

Microbially generated ferruginous crusts: A potential biosignature of continental input in coastal settings

open access: yesSedimentology, EarlyView.
ABSTRACT Thin ferruginous sandy crusts are common on top of sandstone beds in the Early Permian post‐glacial deposits of the Paraná Basin in southern Brazil. These crusts usually preserve wrinkle structures, suggesting that they might be a product of microbial mediation.
Patrícia Weschenfelder   +2 more
wiley   +1 more source

The Chemical Composition of {\tau} Ceti and Possible Effects on Terrestrial Planets

open access: yes, 2015
{\tau} Ceti (HD10700), a G8 dwarf with solar mass of 0.78, is a close (3.65 pc) sun-like star where 5 possibly terrestrial planet candidates (minimum masses of 2, 3.1, 3.5, 4.3, and 6.7 Earth masses) have recently been discovered. We report abundances of
Pagano, Michael   +3 more
core   +1 more source

Oxychlorine Species on Mars: A Review

open access: yesReviews of Geophysics, Volume 63, Issue 4, December 2025.
Abstract Oxychlorine species (mainly perchlorate and chlorate) have been identified at multiple locations on the surface of Mars by both orbiter and in situ rovers. They have also been found in martian meteorites. Cl‐isotopes in meteoritic minerals suggest that an oxychlorine cycle has been operating on the martian surface for the last ∼4 billion years.
Kaushik Mitra
wiley   +1 more source

Utilization of Proteomic Measures for Early Detection of Drug Benefits and Adverse Effects

open access: yesThe Journal of Clinical Pharmacology, Volume 65, Issue 11, Page 1460-1473, November 2025.
Abstract Recognition of benefits and adverse effects of therapies in earlier clinical trial phases could improve the safety, efficiency, and cost of clinical trials. Using four clinical trials representing a diverse set of diseases and drug classes (EXSCEL: exenatide/GLP‐1 RA, SUGAR‐DM‐HF: empagliflozin/SGLT2i, PRADA: epirubicin/anthracycline, and ...
Jessica Chadwick   +17 more
wiley   +1 more source

Mars simulated exposure and the characteristic Raman biosignatures of amino acids and halophilic microbes [PDF]

open access: yes, 2017
Though Raman bands of α-amino acids (AA) are well documented, often only the strongest intensity bands are quoted as identifiers (e.g. Jenkins et al., 2005; De Gelder et al., 2007; Zhu et al., 2011).
Gilmour, I.   +5 more
core  

Evolutionary and functional relationships between plant and microbial C1 metabolism in terrestrial ecosystems

open access: yesNew Phytologist, Volume 248, Issue 3, Page 1132-1153, November 2025.
Summary One‐carbon (C1) metabolism, centered on the universal methyl donor S‐adenosyl methionine (SAM), plays critical roles in biosynthesis, redox regulation, and stress responses across plants and microbes. A recently proposed photosynthetic C1 pathway links SAM methyl groups directly to RuBisCO‐mediated CO2 assimilation and integrates with nitrogen ...
Kolby J. Jardine   +6 more
wiley   +1 more source

Advancements and Challenges in Salivary Metabolomics for Early Detection and Monitoring of Systemic Diseases

open access: yesMedComm, Volume 6, Issue 10, October 2025.
Salivary metabolomics offers a noninvasive and effective approach for early disease detection and monitoring. Salivary metabolites reflect systemic metabolism, inflammation, and external factors such as diet and stress. Advance in bioinformatics and machine learning facilitates the identification of metabolic biomarkers with high diagnostic accuracy ...
Xinyuan Zhao   +8 more
wiley   +1 more source

Biosignatures of Exposure/Transmission and Immunity [PDF]

open access: yesThe American Journal of Tropical Medicine and Hygiene, 2015
A blood test that captures cumulative exposure over time and assesses levels of naturally acquired immunity (NAI) would provide a critical tool to monitor the impact of interventions to reduce malaria transmission and broaden our understanding of how NAI develops around the world as a function of age and exposure. This article describes a collaborative
King, Christopher L   +8 more
openaire   +6 more sources

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