Results 1 to 10 of about 21,799 (237)

Patterns of Tumor Necrosis Factor Inhibitor (TNFi) Biosimilar Use Across United States Rheumatology Practices [PDF]

open access: yesACR Open Rheumatology, 2020
Objective It is unclear if biosimilars of biologics for inflammatory arthritis are realizing their promise to increase competition and improve accessibility.
Nick Bansback   +8 more
doaj   +2 more sources

Adoption of Biosimilar Infliximab for Rheumatoid Arthritis, Ankylosing Spondylitis, and Inflammatory Bowel Diseases in the EU5: A Budget Impact Analysis Using a Delphi Panel [PDF]

open access: yesFrontiers in Pharmacology, 2017
Introduction: Introducing biosimilar infliximab for the treatment in rheumatology (rheumatoid arthritis and ankylosing spondylitis) and inflammatory bowel disease (Crohn's disease and ulcerative colitis) may reduce treatment costs associated with ...
Tim A. Kanters   +5 more
doaj   +7 more sources

Biosimilars [PDF]

open access: yesJournal of the European Academy of Dermatology and Venereology, 2018
Linked article: This is a commentary on P. Yamauchi et al., pp. 1066–1074 in this issue.
Sandeep, Parsad, Chadi, Nabhan
  +13 more sources

Biosimilars [PDF]

open access: yesLupus, 2020
Biological therapies have widened the therapeutic armamentarium for immune-mediated inflammatory diseases, providing in many cases a broad range of treatment options with different mechanisms of action. The widespread use of biological agents in systemic lupus erythematosus is currently limited to belimumab and rituximab, although results of promising
Christopher J Edwards   +1 more
  +6 more sources

Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy

open access: yesmAbs, 2022
The α-Gal epitope consisting of the terminal trisaccharide Galα1,3Galβ1,4GlcNAc exposed on cell or protein surfaces can cause severe immune reactions, such as hypersensitivity reactions, in humans.
Arthur Hinterholzer   +6 more
doaj   +1 more source

An international comparative analysis and roadmap to sustainable biosimilar markets

open access: yesFrontiers in Pharmacology, 2023
Background: Although biosimilar uptake has increased (at a variable pace) in many countries, there have been recent concerns about the long-term sustainability of biosimilar markets.
Khalid A. Alnaqbi   +22 more
doaj   +1 more source

Barriers to Biosimilar Prescribing Incentives in the Context of Clinical Governance in Spain

open access: yesPharmaceuticals, 2021
Incentives contribute to the proper functioning of the broader contracts that regulate the relationships between health systems and professionals.
Félix Lobo, Isabel Río-Álvarez
doaj   +1 more source

Interchangeability of biosimilars: A study of expert views and visions regarding the science and substitution

open access: yesPLoS ONE, 2022
Healthcare systems have reached a critical point regarding the question of whether biosimilar substitution should become common practice. To move the discussion forward, the study objective was to investigate the views of experts from medicines agencies ...
Louise C. Druedahl   +6 more
doaj   +2 more sources

Knowledge and Perception of Iraqi Pharmacists Towards Biosimilar Medicines

open access: yesIraqi Journal of Pharmaceutical Sciences, 2021
Biosimilars are non-innovative copy versions of biologic medicines which are proven to be clinically equivalent to, as effective and as safe as their reference biologics.
Ashwaq J. Mohammed, Dheyaa J. Kadhim
doaj   +1 more source

TNF-alpha inhibitors biosimilar use in France: a nationwide population-based study using the French National Health Data System

open access: yesScientific Reports, 2022
TNF-alpha inhibitors have revolutionized the therapeutic care in chronic inflammatory diseases. Several biosimilar products were commercialized at their patent expiry, substantially decreasing the cost of treatment.
Hugo Jourdain   +3 more
doaj   +1 more source

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