Results 121 to 130 of about 30,003 (287)

Recombinant Human Insulin in Global Diabetes Management – Focus on Clinical Efficacy [PDF]

open access: yes, 2017
Biosynthetic human insulin and insulin analogues are the mainstay of insulin therapy for both type 1 and type 2 diabetes although access to human insulin at affordable prices remains a global issue.
Landgraf, Wolfgang   +3 more
core   +1 more source

The protein science of biosimilars [PDF]

open access: bronze, 2006
Martin K. Kuhlmann, Adrian Covic
openalex   +1 more source

Towards Personalised Therapy in Chronic Spontaneous Urticaria: Advancing From Endotype to Clinical Response

open access: yesClinical &Experimental Allergy, EarlyView.
Chronic spontaneous urticaria (CSU) is a debilitating skin disorder with significant impact upon quality of life. Current guidelines advocate stepwise treatment of standard dose antihistamines, high dose antihistamines, omalizumab and ciclosporin.
Katie Ridge   +7 more
wiley   +1 more source

Ten years of clinical experience with biosimilar human growth hormone: a review of safety data

open access: yesDrug Design, Development and Therapy, 2017
Maria Victoria Borrás Pérez,1 Berit Kriström,2 Tomasz Romer,3 Mieczyslaw Walczak,4 Nadja Höbel,5 Markus Zabransky5 1Hospital General de Granollers, Granollers, Barcelona, Spain; 2Department of Clinical Sciences, Pediatrics, Ume ...
Borrás Pérez MV   +5 more
doaj  

Trading between perceived risks and benefits related to biosimilar biological treatment in Crohn’s disease; discrete choice experiment among gastroenterologists [PDF]

open access: yes, 2015
Objective: The objective of the study is to explore preferences of gastroenterologists for biosimilar drugs in Crohn’s Disease and reveal trade-offs between the perceived risks and benefits related to biosimilar drugs.
Baji, Petra   +7 more
core  

Ustekinumab Biosimilars

open access: yesBiologics
Ustekinumab is a fully human IgG1k monoclonal antibody that binds with high affinity and specificity to the p40 subunit of interleukins (IL-) 12 and 23, inhibiting their activity by preventing binding to their receptors. The European extension of the patent (Supplementary Protection Certificate) of ustekinumab expired on July 20, 2024.
Elena Carmona-Rocha, Lluís Puig
openaire   +2 more sources

The Use of miRNA Panel as a Growth Plate Marker of Short‐Term Response to GH

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Recombinant human growth hormone (GH) therapy shows variable growth responses in patients with growth hormone deficiency (GHD), highlighting the need for reliable biomarkers to predict individual sensitivity. Objective This study investigated circulating microRNAs (miRNAs) involved in growth plate regulation during GH therapy in ...
Caroline Rosa Pellicciari   +8 more
wiley   +1 more source

A Comparison between Recombinant Activated Factor VII (Aryoseven) and Novoseven in Patients with Congenital Factor VII Deficiency [PDF]

open access: yes, 2015
In order to establish the efficacy and biosimilar nature of AryoSeven to NovoSeven in the treatment of congenital factor VII (FVII) deficiency, patients received either agent at 30 1/4g/kg, intravenously per week for 4 weeks, in a randomized fashion. The
Abolghasemi, H.   +16 more
core  

Non‐Clinical Safety Studies on Biosimilar Recombinant Human Erythropoietin [PDF]

open access: bronze, 2007
Michael J. Parnham   +2 more
openalex   +1 more source

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