Results 141 to 150 of about 30,003 (287)

Phenotypic Differences and Clinical Outcomes of South Asian Children With IBD: A Singapore–Malaysia Study From the Asian PIBD Registry Network

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Existing literature largely contrasts pediatric inflammatory bowel disease (PIBD) phenotypic differences and outcomes of South Asians (SAs) with Caucasians. No published comparative data exist between SAs and non‐SAs within Asia‐Pacific.
James Guoxian Huang, Kee Seang Chew, Veena Logarajah, Way Seah Lee, Marion Margaret Aw   +4 more
wiley   +1 more source

Innovator ranibizumab ComparEd to Biosimilar ranibizumab in combination with Expansile gas in submaculaR HemorrhaGe: the ICEBERG study

BMC Ophthalmology
Purpose To compare the anatomical and visual outcomes in eyes with submacular hemorrhage (SMH) treated with a combination of ranibizumab (RBZ) either innovator or biosimilar (Razumab) and intravitreal perfluoropropane gas (C3F8).
Debdulal Chakraborty, Tushar Kanti Sinha, Soumen Mondal, Subhendu Boral, Arnab Das, Saptorshi Majumbar, Angshuman Mukherjee, Ranabir Bhattacharya, Sumit Randhir Singh   +8 more
doaj   +1 more source

Healthy volunteer stem cell donors followed up 10 years after stimulation with biosimilar filgrastim

Transfusion, EarlyView.
Abstract Background The application of granulocyte colony‐stimulating factors (G‐CSF) for mobilizing hematopoietic stem and progenitor cells in healthy donors is considered safe. However, only limited safety information is available about long‐term adverse events (AEs) in this setting.
Jens Heyn, Susanne Bräuninger, Petra Becker, Niklas Stoeckmann, Christian Seidl, Sebastian Howe, Simon Daubert, Daniel Fürst, Hubert Schrezenmeier, Halvard Bonig   +9 more
wiley   +1 more source

Growth hormone receptor antagonists, GHA2 and GHA3, with dual activity against the human and mouse receptor

Protein Science, Volume 34, Issue 8, August 2025.
Abstract Aberrant human growth hormone (GH) expression has been increasingly linked to poor outcomes in certain cancers and reduced health span. GH receptor (GHR) signal transduction activates signaling pathways that promote cell proliferation and survival, contributing to tumor progression.
Yue Wang, Ries J. Langley, Julia Harms, Theo Portlock, Stephen M. F. Jamieson, Jo K. Perry   +5 more
wiley   +1 more source

Response to ‘Not all new recombinant human erythropoietins are biosimilars’ [PDF]

, 2009
Sai Ram Keithi-Reddy, Ajay Singh
openalex   +1 more source

Photocatalytic Diselenide Contraction as a Tool for Site‐Selective Isosteric Ubiquitylation

Journal of Peptide Science, Volume 31, Issue 8, August 2025.
Chemoselective photocatalytic diselenide contraction (PDC) enables site‐selective biomimetic ubiquitylation of substrate peptides. The resulting selenalysine linkage undergoes efficient cleavage by deubiquitylating enzymes. ABSTRACT Ubiquitylation is a highly conserved post‐translational modification (PTM) in eukaryotes, which serves as a critical ...
Herwig Weissinger, Moritz Urschbach, Luca Ferrari, Sascha Martens, Christian F. W. Becker   +4 more
wiley   +1 more source

A cost-effectiveness evaluation of the originator follitropin alpha compared to the biosimilars for assisted reproduction in Germany

International Journal of Women's Health, 2019
Weiguang Xue,1 Adam Lloyd,1 Edel Falla,1 Claudia Roeder,2 Rudiger Papsch,2 Klaus Bühler3,41IQVIA, Real-World Evidence, London, UK; 2Merck KGaA, Frankfurt, Germany; 3Centre for Gynecology Endocrinology & Reproductive Medicine Kinderwunsch-Zentrum
Xue W, Lloyd A, Falla E, Roeder C, Papsch R, Bühler K   +5 more
doaj  

Rapid comparison of a candidate biosimilar to an innovator monoclonal antibody with advanced liquid chromatography and mass spectrometry technologies [PDF]

, 2010
Hongwei Xie, Asish Chakraborty, Joomi Ahn, Ying Yu, Deepalakshmi P. Dakshinamoorthy, Martin Gilár, Weibin Chen, St John Skilton, Jeffery R. Mazzeo   +8 more
openalex   +1 more source

The Optimal Timing and Duration of Daily G‐CSF for the Primary Prevention of Febrile Neutropenia in Breast Cancer Patients Undergoing Adjuvant TAC Chemotherapy

Asia-Pacific Journal of Clinical Oncology, Volume 21, Issue 4, Page 383-391, August 2025.
The study aimed to determine the optimal timing and duration of filgrastim administration for the primary prevention of febrile neutropenia (FN) in breast cancer patients undergoing adjuvant TAC chemotherapy. Our findings suggest that initiating daily filgrastim from Day 2 and continuing for 7 days optimizes toxicity reduction.
Zisun Kim, Sung Mo Hur, Jong Eun Lee, Sun Wook Han, Hae Il Jung, Sung Yong Kim, Jihyoun Lee, Cheol Wan Lim   +7 more
wiley   +1 more source

Biosimilar medicines: creating sustainable competition in an era of a new patent cliff in biological medicines

Journal of Pharmaceutical Policy and Practice, 2015
Maarten Van Baelen
doaj   +1 more source