Biotech drugs : biological therapeutic agents [PDF]
, 2009 The recent years has seen significant growth in a new therapeutic approach to the management of disease. Biological therapeutic agents, constitute a broad category of drugs, usually generated by recombinant techniques from living organisms.
Fenech, Anthony G., Grech, Godfrey
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Cancer Science, EarlyView.J‐MIND evaluated the safety and tolerability of tafasitamab, a CD19‐targeting monoclonal antibody, alone or in combination with other therapies in Japanese patients with B‐cell non‐Hodgkin lymphoma (NHL). Most common treatment‐emergent adverse events across all groups were hematological, and no serious tafasitamab treatment‐related or fatal adverse ...
Koji Izutsu +7 more
wiley +1 more source
Bioethical issues in the development of biopharmaceuticals [PDF]
, 2012 Development of biopharmaceuticals is a challenging issue in bioethics. Unlike conventional, small molecular weight drugs, biopharmaceuticals are proteins derived from DNA technology and hybrid techniques with complex three dimensional structures ...
Protić Dragana, Todorović Zoran
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Impact of adalimumab treatment on impairment of non‐professional activities in psoriasis patients
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and objectives Psoriasis can result in reduced quality of life, work productivity loss, and a significant restriction in non‐professional activities. This study investigates the effects of long‐term treatment with adalimumab regarding work ability, non‐professional activities, and health‐related quality of life in a large real‐word ...
Georgios Kokolakis +4 more
wiley +1 more source
Sovereign Immunity for Rent: How the Commodification of Tribal Sovereign Immunity Reflects the Failures of the U.S. Patent System [PDF]
, 2019 Last year, a Fortune 500 pharmaceutical company attempted to rent the sovereign immunity of an American Indian tribe in order to shield its patents on a dry-eye drug from invalidation by generic competitors in inter partes review.
Geddes, Katrina G
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Bioequivalence of HX575 (recombinant human epoetin alfa) and a comparator epoetin alfa after multiple intravenous administrations: an open-label randomised controlled trial [PDF]
, 2009 Conclusions: HX575 and the comparator epoetin alfa were bioequivalent with respect to their PK/PD, supporting the conclusion that both, when administered subcutaneously, will be equally efficacious and may be interchangeable as therapy.
Fritz Sörgel +4 more
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Transfusion, EarlyView.Abstract Background Heparin combined with sodium citrate has been used in leukocytapheresis for pediatric patients. Since 2022, we have performed leukocytapheresis using a highly concentrated sodium citrate solution (HSC, 5.32%) instead of acid citrate dextrose solution A (ACD‐A).
Keiko Fujii +8 more
wiley +1 more source
An overall comparison of small molecules and large biologics in ADME testing [PDF]
, 2016 Biologics mainly monoclonal antibodies (mAbs) and antibody-drug conjugates (ADCs) as new therapeutics are becoming increasingly important biotherapeutics.
Hong Wan
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Exploring Affordable Curative Therapy for Sickle Cell Disease in Africa: A Comprehensive Overview
American Journal of Hematology, Volume 101, Issue S1, Page 56-74, April 2026.ABSTRACT The practical aspects of developing curative treatments for sickle cell disease (SCD) in Africa, such as gene therapy and hematopoietic stem cell transplantation, involve strengthening healthcare infrastructure, training healthcare professionals, establishing regional treatment centers, and creating national SCD programs.
Adetola A. Kassim +2 more
wiley +1 more source
Immunoteràpia, un concepte clàssic amb novetats rellevants: els biològics i la immunoteràpia antitumoral com a exemples concrets [PDF]
, 2014 De la inducció de memòria immunitària de les vacunes antiinfeccioses, a la immunoteràpia cel·lular i genètica per al tractament de tumors, el ventall de teràpies potencials a través de la modulació del sistema immunitari és una de les aproximacions més ...
Caballero Baños, Miguel +3 more
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