Results 31 to 40 of about 790,096 (261)
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur®) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency [PDF]
Pharmaceutics, 2022 Recombinant human follicle stimulating hormone (r-hFSH) is widely used for infertility treatment and is subject to the development of biosimilars. There are different purification strategies that can yield r-hFSH of pharmaceutical quality from Chinese hamster ovary cell culture broth.
Maria Sinegubova +6 more
openaire +3 more sources
Fine Chemical Technologies, 2021 Objectives. In this biosimilar research, we compare the monoclonal antibody eculizumab obtained from different drugs [original Soliris® (Alexion Pharmaceuticals) and candidate Elizaria® (Generium)] by intact mass measurement and middle-up mass ...
M. Degterev, R. Shukurov
semanticscholar +1 more source
Biosimilar Agents for Psoriasis Treatment: The Perspective of Portuguese Patients
Acta Médica Portuguesa, 2018 Introduction: Biosimilars are highly similar copies of previously approved original biologic medicines. Their introduction on the market may yield cost reduction.
Alexandra Azevedo +3 more
doaj +1 more source
Ten years' clinical experience with biosimilar human growth hormone: a review of efficacy data [PDF]
, 2017 In 2006, the European Medicines Agency (EMA) approved Omnitrope(®) as a biosimilar recombinant human growth hormone (rhGH), on the basis of comparable quality, safety, and efficacy to the reference medicine (Genotropin(®), Pfizer).
Zabransky, Markus +11 more
core +1 more source
Acknowledgment to Reviewers of Pharmaceuticals in 2020
, 2021 Peer review is the driving force of journal development, and reviewers are gatekeepers who ensure that Pharmaceuticals maintains its standards for the high quality of its published papers [...
Pharmaceuticals Editorial Office Pharmaceuticals Editorial Office
core +1 more source
Biosimilar tenecteplase versus alteplase in acute ischemic stroke: A real world study
Annals of Indian Academy of Neurology, 2023 Background and Purpose: There is an unmet need for a more effective thrombolytic agent in acute ischemic stroke (AIS) management. Various studies and meta-analysis suggest tenecteplase (TNK) as non-inferior over alteplase (rTPA).
Ayush Mohan +11 more
doaj +1 more source
Ten years of biosimilar recombinant human growth hormone in Europe [PDF]
, 2017 Paul Saenger Division of Pediatric Endocrinology, Department of Pediatrics, Winthrop University Hospital, Mineola, NY, USA Abstract: Recombinant human growth hormone (rhGH) has been in clinical use for more than 30 years.
Saenger P, Paul Saenger
core +1 more source
Medicines under additional monitoring in the European Union [PDF]
Farmacia Hospitalaria, 2019 Objective: The objective of this study was to analyse the characteristics of medicines subject to additional monitoring. We assessed the following aspects: the criteria applied to approve a medicine as being subject to additional monitoring; the ...
Esther Salgueiro +5 more
doaj +1 more source
Biosimilar medicines and cost-effectiveness
, 2011 Steven SimoensResearch Centre for Pharmaceutical Care and Pharmaco-economics, Faculty of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, BelgiumAbstract: Given that biosimilars are agents that are similar but not identical to the ...
Steven Simoens
core +1 more source