Results 141 to 150 of about 39,064 (303)
JAAD International, 2020 Background: As biosimilars have become available in various parts of the world, the International Psoriasis Council has reviewed aspects of their use.
Arnon D. Cohen, MD, MPH, PhD +8 more
doaj
Era of biosimilars in rheumatology: reshaping the healthcare environment
RMD Open, 2019 Compared with the original approved biological drug on which it is based, a biosimilar has highly similar physicochemical characteristics and biological activity, as well as equivalent efficacy and no clinically meaningful differences in safety and ...
J. Smolen +4 more
semanticscholar +1 more source
Acta Ophthalmologica, EarlyView.Abstract The aim of this review was to evaluate the comparative efficacy of intravitreal anti‐vascular endothelial growth factor (anti‐VEGF) therapy for neovascular AMD. We searched 12 literature databases for randomised clinical trials (RCT) on anti‐VEGF therapy for neovascular AMD and extracted data on: change from baseline to 12 months in best ...
Emilie T. S. Butler +17 more
wiley +1 more source
Biosimilar insulins: Narrative review of the regulatory framework and registration studies. [PDF]
Diabetes Obes MetabAbstract Biosimilar insulins have been commercially available in the EU since 2014. Currently, six biosimilar insulins are approved in the EU and four in the US. However, commercial success has been limited, which may be in part due to concerns among physicians and people with diabetes that biosimilar insulins are substandard in efficacy, safety, and ...
Heise T, DeVries JH.
europepmc +2 more sources
Biosimilars: How similar or dissimilar are they? (Review Article) [PDF]
, 2006 Simon D. Roger
openalex +1 more source
The impact of the Medicines Control Council backlog and fast-track review system on access to innovative and new generic and biosimilar medicines of public health importance in South Africa [PDF]
, 2016 The fast-track registration policy of the South African National Department of Health allows for rapid registration of new medicines of public health importance and of all medicines on the Essential Medicines List, most of which are generics. No limit is
Leng, HMJ, Pollock, AM, Sanders, D
core +3 more sources
Meta‐Analysis: Intravenous Versus Subcutaneous Infliximab in Inflammatory Bowel Disease
Alimentary Pharmacology &Therapeutics, EarlyView.There is uncertainty about the relative efficacy of subcutaneous (SC) compared to intravenous (IV) infliximab in inflammatory bowel disease (IBD). In this network meta‐analysis, SC infliximab was associated with high efficacy rates in IBD use, with a suggestion of clinical benefit above the IV formulation.
John David Chetwood +4 more
wiley +1 more source
Clinical &Experimental Allergy, EarlyView.Chronic spontaneous urticaria (CSU) is a debilitating skin disorder with significant impact upon quality of life. Current guidelines advocate stepwise treatment of standard dose antihistamines, high dose antihistamines, omalizumab and ciclosporin.
Katie Ridge +7 more
wiley +1 more source
The Use of miRNA Panel as a Growth Plate Marker of Short‐Term Response to GH
Clinical Endocrinology, EarlyView.ABSTRACT Introduction Recombinant human growth hormone (GH) therapy shows variable growth responses in patients with growth hormone deficiency (GHD), highlighting the need for reliable biomarkers to predict individual sensitivity. Objective This study investigated circulating microRNAs (miRNAs) involved in growth plate regulation during GH therapy in ...
Caroline Rosa Pellicciari +8 more
wiley +1 more source
Clinical &Experimental Ophthalmology, EarlyView.ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano +40 more
wiley +1 more source