Results 101 to 110 of about 373,154 (280)

Comparative effectiveness and safety of oral anticoagulants in patients with atrial fibrillation using antiarrhythmic drugs: An international cohort study

British Journal of Clinical Pharmacology, EarlyView.
Aim Our international cohort study assessed the comparative effectiveness and safety of direct oral anticoagulants (DOACs) and vitamin K antagonists (VKAs) among patients with non‐valvular atrial fibrillation (NVAF) using antiarrhythmic drugs. Methods Using the United Kingdom's (UK's) Clinical Practice Research Datalink Aurum and Québec claims data, we
Fabian Maximilian Meinert, Jenny Dimakos, Ying Cui, Kristian B. Filion, Christel Renoux, Antonios Douros   +5 more
wiley   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Risk of cardiac, neuropsychiatric and musculoskeletal adverse events with levothyroxine: Systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Levothyroxine (LT4) is the standard treatment for hypothyroidism and the most widely prescribed medication worldwide. Although generally safe, regulatory reports list potential cardiac, neuropsychiatric and musculoskeletal adverse events (AEs). Clarifying their clinical relevance is essential.
Bala Swetha Baskaran, Mohammad Ali Omrani, Flory T. Muanda   +2 more
wiley   +1 more source

Biostatistical approaches for the reconstruction of gene co-expression networks based on transcriptomic data [PDF]

, 2013
Liliana López-Kleine, Letícia Ferro Leal, Camilo López   +2 more
openalex   +1 more source

Extremity Function After Transfemoral Transcatheter Aortic Valve Implantation: A TAVI XS Sub‐Study

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Physical decline after transcatheter aortic valve implantation (TAVI) is associated with worse outcomes. However, data on post‐TAVI extremity function are limited. This sub‐study of the TAVI XS trial aimed to assess extremity function after transfemoral TAVI, evaluate functional decline, compare outcomes between upper‐and lower ...
Geert A. A. Versteeg, Maxim J. P. Rooijakkers, Kimberley I. Hemelrijk, Pieter J. Vlaar, Daniël C. Overduin, Marleen H. van Wely, Hugo M. Aarts, Dirk‐Jan van Ginkel, Niels A. Stens, Lokien X. van Nunen, Robert Jan van Geuns, Leen A. F. M. van Garsse, Guillaume S. C. Geuzebroek, Michel W. A. Verkroost, Aysun Cetinyurek‐Yavuz, Robin H. Heijmen, Dick H. J. Thijssen, Jurrien M. ten Berg, Pim A. L. Tonino, Ronak Delewi, Niels van Royen   +20 more
wiley   +1 more source

Annals of Biostatistics & Biometric Applications

, 2019

openalex   +1 more source

Review of Regression Methods in Biostatistics: Linear, Logistic, Survival, and Repeated Measures Models by Vittinghoff, Glidden, Shiboski, and McCulloch [PDF]

, 2005
Stanley Lemeshow, Melvin L. Moeschberger
openalex   +1 more source

Rank‐based estimation of propensity score weights via subclassification

Canadian Journal of Statistics, EarlyView.
Abstract Propensity score (PS) weighting estimators are widely used for causal effect estimation and enjoy desirable theoretical properties, such as consistency and potential efficiency under correct model specification. However, their performance can degrade in practice due to sensitivity to PS model misspecification.
Linbo Wang, Yuexia Zhang, Thomas S. Richardson, Xiaohua Zhou   +3 more
wiley   +1 more source

Creating biostatistics web application for quantitative data analysis using R Shiny

, 2022
Toluay, Tanya Deniz
openalex   +1 more source

Predicting cervical cancer DNA methylation from genetic data using multivariate CMMP

Canadian Journal of Statistics, EarlyView.
Abstract Epigenetic modifications link the environment to gene expression and play a crucial role in tumour development. DNA methylation, in particular, is gaining attention in cancer research, including cervical cancer, the focus of this study.
Hang Zhang, Steven Chen, Raymond Balise, Jiming Jiang, Nagi Ayad, J. Sunil Rao   +5 more
wiley   +1 more source