Results 231 to 240 of about 378,886 (332)

CRISPR Screens Identify PIK3C2A as a Novel Mediator of EGFR Inhibitor Resistance in Head and Neck Squamous Cell Carcinoma

Head &Neck, EarlyView.
ABSTRACT Background Head and neck squamous cell carcinoma (HNSCC) is a malignancy with poor prognosis and survival. While epidermal growth factor receptor (EGFR) is a known driver of HNSCC, EGFR inhibitors show limited efficacy as monotherapies, suggesting that effective combination therapies are needed.
Jiayu Wang, Megan L. Ludwig, Aditi Kulkarni, Andrew C. Birkeland, Nicole L. Michmerhuizen, Elizabeth Gensterblum‐Miller, Jingyi Zhai, Hui Jiang, Paul Swiecicki, Marisa Buchakjian, Molly Heft Neal, Steven B. Chinn, Matthew E. Spector, J. Chad Brenner   +13 more
wiley   +1 more source

Correction: Hyperbaric Oxygen Therapy for Severe Pediatric Traumatic Brain Injury: A Secondary Psychometric and Nonparametric Analysis of a Retrospective Case Series. [PDF]

Cureus
Peterson T, Burgin S, Sherwin R, Strale F.   +3 more
europepmc   +1 more source

Contribution of Biostatistics in Clinical Trials to Human Society: Experience of a Quarter of a Century and the Future Prospects

, 2007
Yasuo Ohashi
openalex   +2 more sources

Genetically determined body mass index is associated with diffuse large B‐cell lymphoma in polygenic and Mendelian randomization analyses

International Journal of Cancer, EarlyView.
What's New? Obesity has been linked to the risk of non‐Hodgkin lymphoma (NHL), but the evidence remains inconclusive. Here, the authors investigate the possibility of shared genetic risk factors between obesity and four common NHL types. Drawing on data from 8 genome‐wide association studies, they found that a higher genetically determined BMI was ...
Amy Moore, Eleanor Kane, Lauren R. Teras, Mitchell J. Machiela, Joshua Arias, Orestis A. Panagiotou, Alain Monnereau, Nicole Wong Doo, Zhaoming Wang, Susan L. Slager, Roel C. H. Vermeulen, Claire M. Vajdic, Karin E. Smedby, John J. Spinelli, Joseph Vijai, Graham G. Giles, Brian K. Link, Alan A. Arslan, Alexandra Nieters, Paige M. Bracci, Nicola J. Camp, Gilles Salles, Wendy Cozen, Henrik Hjalgrim, Immaculata De Vivo, Hans‐Olov Adami, Demetrius Albanes, Nikolaus Becker, Yolanda Benavente, Simonetta Bisanzi, Paolo Boffetta, Paul Brennan, Angela R. Brooks‐Wilson, Federico Canzian, Jacqueline Clavel, Lucia Conde, David G. Cox, Karen Curtin, Lenka Foretova, Hervé Ghesquières, Bengt Glimelius, Thomas M. Habermann, Jonathan N. Hofmann, Qing Lan, Mark Liebow, Anne Lincoln, Marc Maynadie, James McKay, Mads Melbye, Lucia Miligi, Roger L. Milne, Thierry J. Molina, Lindsay M. Morton, Kari E. North, Kenneth Offit, Marina Padoan, Sara Piro, Alpa V. Patel, Mark P. Purdue, Vignesh Ravichandran, Elio Riboli, Richard K. Severson, Melissa C. Southey, Anthony Staines, Lesley F. Tinker, Ruth C. Travis, Sophia S. Wang, Elisabete Weiderpass, Stephanie Weinstein, Tongzhang Zheng, Stephen J. Chanock, Nathaniel Rothman, Brenda M. Birmann, James R. Cerhan, Sonja I. Berndt   +74 more
wiley   +1 more source

Common Statistical Pitfalls in Basic Science Research

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
Lisa M. Sullivan, Janice Weinberg, John F. Keaney   +2 more
doaj   +1 more source

Correction: Review of Recent Pharmacoepidemiologic Post-Market Safety Studies Through the Lens of the Estimand Framework. [PDF]

Ther Innov Regul Sci
Ma Y, Haddad J, Liu W, Snyder E, Bennett D, Mayo S.   +5 more
europepmc   +1 more source

Circulating fatty acid binding protein 4 (FABP‐4) concentrations and mortality in individuals with colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

International Journal of Cancer, EarlyView.
What's New? Higher pre‐diagnostic body mass index has been associated with higher risk of mortality in individuals with colorectal cancer; however, the mechanism remains unclear. This prospective analysis of incident colorectal cancer cases within the European Prospective Investigation into Cancer and Nutrition cohort study addressed potential collider
Thu Thi Pham, Katharina Nimptsch, Krasimira Aleksandrova, Mazda Jenab, Veronika Fedirko, Anja Olsen, Anne Tjønneland, Claire Cadeau, Gianluca Severi, Matthias B. Schulze, Renée Turzanski Fortner, Verena Katzke, Claudia Agnoli, Carlotta Sacerdote, Rosario Tumino, Simona Signoriello, Camino Trobajo‐Sanmartín, Jesús‐Humberto Gómez, María‐Dolores Chirlaque, Maria‐Jose Sánchez, Marta Crous‐Bou, Anne May, Alicia Heath, Dagfinn Aune, Elisabete Weiderpass, Tobias Pischon   +25 more
wiley   +1 more source

Correction: Evaluation of the SOFA score as a tool to predict DCI-associated infarctions after spontaneous subarachnoid hemorrhage. [PDF]

Front Med (Lausanne)
Kurz E, Fassl V, Brockmann C, Schulze A, Kalasauskas D, Ringel F, Neulen A.   +6 more
europepmc   +1 more source

Body height and the excess cancer risk in men

International Journal of Cancer, EarlyView.
What's New? In cancers that affect both sexes, men usually have a higher risk than women. While this is often attributed to behavioral factors, such as exposure to environmental carcinogens, there may be an intrinsic biological mechanism involved. Tall stature has been associated with increased cancer risk.
Cecilia Radkiewicz, Gustaf Edgren, Arvid Sjölander, Emelie Benyi, Mats Lambe, Paul W. Dickman, Lars Sävendahl   +6 more
wiley   +1 more source

Author Correction: MOADE: a multimodal autoencoder for dissociating bulk multi-omics data. [PDF]

Genome Biol
Sun J, Malik AA, Lin T, Bratton A, Pan Y, Smith K, Onar-Thomas A, Robinson GW, Zhang W, Northcott PA, Li Q.   +10 more
europepmc   +1 more source