Results 161 to 170 of about 1,499,955 (388)

Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications

Advanced Sustainable Systems, EarlyView.
The insect‐microbe interplay fulfills a key ecological role involving the degradation of ligninocellulose biomass. This is coordinated by the secretion of different kinds of proteins, of which ligninolytic enzymes, such as laccases (Lacs), are of prime importance.
Michael Dare Asemoloye, Adeyinka Michael Gbadebo, Tunde Sheriffdeen Bello, Olumayowa Mary Olowe, Akinlolu Olalekan Akanmu, Marta Elisabetta Eleonora Temporiti, Adeyinka Odebode, Segun Oladiran Babarinde, Tsigereda Weldemichael, Leonard Chitongo, Solveig Tosi, Mario Andrea Marchisio   +11 more
wiley   +1 more source

ON THE BIOSYNTHESIS OF CAROTENOIDS [PDF]

Journal of Biological Chemistry, 1954
C. O. Chichester, G. Mackinney, Patricia S. Wong   +2 more
openaire   +5 more sources

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

Advanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu, Jingyi Liu, Wei Qin, Chengsheng Ding, Zhenghao Cai, Duohuo Shu, Hao Zhong, Yanyan Hu, Mengqin Yu, Leqi Zhou, Jianwen Li, Minhua Zheng, Bin Li, Sen Zhang, Xiao Yang, Bo Feng   +15 more
wiley   +1 more source

Analysing a Group of Homologous BAHD Enzymes Provides Insights into the Evolutionary Transition of Rosmarinic Acid Synthases from Hydroxycinnamoyl-CoA:Shikimate/Quinate Hydroxycinnamoyl Transferases

Plants
The interplay of various enzymes and compounds gives rise to the intricate secondary metabolic networks observed today. However, the current understanding of their formation and expansion remains limited. BAHD acyltransferases play important roles in the
Jiali Zhou, Xiaofang Zou, Zixin Deng, Lian Duan   +3 more
doaj   +1 more source

THE BIOSYNTHESIS OF SUCROSE¹ [PDF]

, 1953
Luis F. Leloir, Carlos E. Cardini
openalex   +1 more source

Mycotoxins - Their Biosynthesis in Fungi: Biosynthesis of the Trichothecenes

Journal of Food Protection, 1979
The biosynthetic pathway as currently postulated for trichothecin, a model 12,13-epoxy-Δ9-trichothecene, involves the following sequence: 3 mevalonic acids → farnesyl pyrophosphate → trichodiene → trichodiol → 12,13-epoxytrichothec-9-ene → trichodermol → 12,13-epoxy,4β, 8a-dihydroxy-trichothec-9-ene → trichothecolone → trichothecin.
openaire   +3 more sources

NAD+‐Boosters Improve Mitochondria Quality Control In Parkinson's Disease Models Via Mitochondrial UPR

Advanced Science, EarlyView.
Treatment of MPTP‐incubated cells with NAD+‐boosters increase the UPRmt/mitophagy‐related mitochondria quality control (MQC). Disturbed plasma UPRmt‐mitophagy‐mediated MQC profiles in PD patient samples. NMN inhibits motor deficit and forestalls neuropathology phenotypes of PD mice, which is required the atf4‐medicated UPRmt pathway.
Shuoting Zhou, Xi Xiong, Jialong Hou, Qi Duan, Yi Zheng, Tao Jiang, Jiani Huang, Haijun He, Jiaxue Xu, Keke Chen, Wenwen Wang, Jinlai Cai, Jingjing Qian, Huijun Chen, Weihong Song, XinShi Wang, Chenglong Xie   +16 more
wiley   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Deep Learning-Based Self-Adaptive Evolution of Enzymes

Pharmaceutical Fronts
Biocatalysis has been widely used to prepare drug leads and intermediates. Enzymatic synthesis has advantages, mainly in terms of strict chirality and regional selectivity compared with chemical methods.
Shuiqin Jiang, Dong Yi
doaj   +1 more source

Studies on the biosynthesis of cholesterol. 4. Degradation of rings C and D [PDF]

, 1957
J. W. Cornforth, Irene Youhotsky Gore, G. Popják   +2 more
openalex   +1 more source