Results 231 to 240 of about 620,460 (320)

Antagonist Targeting the Species‐Specific Fatty Acid Dehydrogenase/Isomerase FabX for Anti‐H. pylori Infection

Advanced Science, EarlyView.
This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang, Xiaoxue Ruan, Xudong Hang, Ding Heng, Chang Cai, Liping Zeng, Guoxin Zhang, Lu Zhou, Hongkai Bi, Liang Zhang   +9 more
wiley   +1 more source

Plant Secondary Metabolites-Central Regulators Against Abiotic and Biotic Stresses. [PDF]

Metabolites
Khan A, Kanwal F, Ullah S, Fahad M, Tariq L, Altaf MT, Riaz A, Zhang G.   +7 more
europepmc   +1 more source

VITAMIN B12 AND PROTEIN BIOSYNTHESIS

, 1958
S.R. Wagle, Ranjan Mehta, B. Connor Johnson   +2 more
openalex   +2 more sources

BIOSYNTHESIS OF DICARBOXYLIC ACIDS BY CARBON DIOXIDE FIXATION

, 1950
Joao Baptista Veiga Salles, Severo Ochoa
openalex   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

Advanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye   +8 more
wiley   +1 more source

Phenotypic, Physiological, and Transcriptomic Analyses Reveal Different Responses to Salt Stress in Cultivated Red Lettuce and Wild Lettuce Seedlings. [PDF]

Int J Mol Sci
Chen W, Lian J, Hong C, Sun S, Hao J, Huang S, Wang J, Guan Y, Lu Z, Wang Z, Zhu S, Wei Z.   +11 more
europepmc   +1 more source

Mitofusin 1 Drives Preimplantation Development by Enhancing Chromatin Incorporation of Histone H3.3

Advanced Science, EarlyView.
MFN1 exerts its function partially through histone H3.3 in early embryos. MFN1 colocalizes with PADI6, and its deficiency results in compromised cytoplasmic lattices and ribosomal subunits, leading to declined H3.3 protein level. This, in turn, hinders the incorporation of H3.3 into the embryonic genome, thereby causing failure of male pronucleus ...
Xiao‐yan Shi, Yu Tian, Yu‐fan Wang, Yi‐ran Zhang, Ying Yin, Qing Tian, Lei Li, Bing‐xin Ma, Ximiao He, Li‐quan Zhou   +9 more
wiley   +1 more source

Paclobutrazol induces triterpenoid biosynthesis via downregulation of the negative transcriptional regulator SlMYB in Sanghuangporus lonicericola. [PDF]

Commun Biol
Zhang DX, Liu BY, Xue FF, Tang YL, Yan MJ, Wang SX, Guo L, Tong T, Wan LN, Liu YN, Wang XL, Liu GQ.   +11 more
europepmc   +1 more source

THE BIOSYNTHESIS OF HISTIDINE: d-erythro-IMIDAZOLE-GLYCEROL PHOSPHATE DEHYDRASE

, 1957
Bruce N. Ames
openalex   +1 more source

Vessel‐On‐A‐Chip Coupled Proteomics Reveal Pressure‐Overload‐Induced Vascular Remodeling

Advanced Science, EarlyView.
A vessel‐on‐a‐chip system is developed to replicate both physiological and pathological vessel cyclic stretches. Proteomic analysis reveals pressure‐overload‐induced vascular remodeling, including cellular response to mechanical cues, cellular oxidative stresses, ER stress, and ceramide biosynthesis activation in the vessel‐on‐a‐chip system, well ...
Yanjun Liu, Jianxujie Zheng, Lingyan Zhong, Zengyu Wang, Dan Zhao, Hong Lin, Xiaoxue Zhang, Ke Meng, Xiaoxia Yang, Dongxue Zhang, Ling Lin, Liang Qiao   +11 more
wiley   +1 more source