Results 121 to 130 of about 2,128,798 (360)
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Current research in biotechnology: Exploring the biotech forefront
Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and journals.
Andy Wai Kan Yeung+36 more
doaj
Biotechnology of coconut (Cocos nucifera L.) is a relatively recent area compared to similar work in other crops. It started as tissue culture in the eighties, which led to the development of molecular markers in late nineties with the use of RAPDs ...
V A Parthasarathy+2 more
doaj +1 more source
The roles and applications of extracellular vesicles in cancer
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley +1 more source
Ethical issues of biotechnological human design
Intensive development of biotechnology problematize the boundaries between the phenomenon of technological artifacts and natural objects. Intensive development of biotechnology problematize the boundaries between the phenomenon of technological artifacts
O V Popova
doaj
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Cuba: the strategic choice of advanced scientific development, 1959-2014 [PDF]
Cuba is continuing attracting the attention of the international scientific community for some important and unexpected achievements in applied science such as health biotechnology. They represent outcomes of the 1959 decision of Cuba to develop an advanced scientific system in order to address the most urgent problems for the development of the ...
arxiv
Potential Impacts of Artificial Intelligence (AI) in Biotechnology
The impact of artificial intelligence (AI) in biotechnology has become increasingly significant, driving advancements across multiple subfields in several areas of science.
Alexandrina Gomes+5 more
doaj +1 more source
Stimuliert der BioRegio-Wettbewerb die Bildung von Biotechnologieclustern in Deutschland? [PDF]
Regions with biotechnology-specific knowledge seem to have best chances to attract potential entrepreneurs to establish a biotechnology-firm. Furthermore, regional oriented technology policy is supposed to stimulate the creation process of biotechnology ...
Engel, Dirk, Heneric, Oliver
core
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source