Results 151 to 160 of about 2,525,099 (341)
Application of Biotechnology to Solve Relevant Biological Problems Promotes Understanding of Underlying Concepts [PDF]
, 2001 Although some efforts have been made to modify the curriculum of the Introductory Biology laboratories from a passive to a more experimental form, the use of modern biotechnology had not been implemented at our institution.
Burrowes, P. A., Nazario, G. M.
core +1 more source
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
Biotechnology for developing-country agriculture: problems and opportunities [PDF]
Contents: Brief 1. Overview / Gabrielle J. Persley and John J. Doyle Brief 2. Biotechnology and food and nutrition needs / Richard Flavell Brief 3. Biotechnology and animal vaccines / W. Ivan Morrison Brief 4. The role of the private sector / Clive James
Persley, Gabrielle J. (Gabrielle Josephine), ed.
core
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava +3 more
wiley +1 more source
Cotton, biotechnology, and economic development [PDF]
During the past decade, cotton prices remained considerably below other agricultural prices (although they recovered toward the end of 2010). Yet, between 2000-04 and 2005-09 world cotton production increased 13 percent.
Baffes, John
core
FEBS Open Bio, EarlyView.KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source