Results 31 to 40 of about 1,393,651 (267)
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Open avenues for carotenoid biofortification of plant tissues
Plant carotenoids are plastidial isoprenoids that function as photoprotectants, pigments, and precursors of apocarotenoids such as the hormones abscisic acid and strigolactones. Humans do not produce carotenoids but need to obtain them from their diet as
Luca Morelli +1 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Genetic modification techniques are now well established in agriculture (Brooks and Barfoot, 2009; James, 2010). The same extensive commercial application of genetic modification has not been seen in horticulture and floriculture, with the exception of ...
S.F. Chandler
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Regionalne zróżnicowanie rozwoju biotechnologii w Europie
Modern biotechnology is widely regarded as information technology, a new wave of knowledge-based economy. It is one of the key technologies of the 20th century, with potentially a versatile range of applications, such as healthcare, agriculture and ...
Sławomir Dorocki +1 more
doaj +1 more source
Deep mutational scanning: A versatile tool in systematically mapping genotypes to phenotypes
Unveiling how genetic variations lead to phenotypic variations is one of the key questions in evolutionary biology, genetics, and biomedical research.
Huijin Wei +4 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Current research in biotechnology: Exploring the biotech forefront
Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and journals.
Andy Wai Kan Yeung +36 more
doaj +1 more source
Den groteske Jegeren
Jegeren: En fortelling fra skogen (2015) av Per Dybvig er ei bildebok og kunstbok som viser gnager-lignende dyr med overraskende utvekster på kroppen. Grotesk estetikk og ulike typer hybriditet er gjennomgående i verket, samt bildekomponenter som innbyr ...
Helge Ridderstrøm
doaj +1 more source

