Results 31 to 40 of about 1,393,651 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Open avenues for carotenoid biofortification of plant tissues

open access: yesPlant Communications, 2023
Plant carotenoids are plastidial isoprenoids that function as photoprotectants, pigments, and precursors of apocarotenoids such as the hormones abscisic acid and strigolactones. Humans do not produce carotenoids but need to obtain them from their diet as
Luca Morelli   +1 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Biotechnology in floriculture

open access: yesІнтродукція Рослин, 2010
Genetic modification techniques are now well established in agriculture (Brooks and Barfoot, 2009; James, 2010). The same extensive commercial application of genetic modification has not been seen in horticulture and floriculture, with the exception of ...
S.F. Chandler
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Regionalne zróżnicowanie rozwoju biotechnologii w Europie

open access: yesPrace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, 2012
Modern biotechnology is widely regarded as information technology, a new wave of knowledge-based economy. It is one of the key technologies of the 20th century, with potentially a versatile range of applications, such as healthcare, agriculture and ...
Sławomir Dorocki   +1 more
doaj   +1 more source

Deep mutational scanning: A versatile tool in systematically mapping genotypes to phenotypes

open access: yesFrontiers in Genetics, 2023
Unveiling how genetic variations lead to phenotypic variations is one of the key questions in evolutionary biology, genetics, and biomedical research.
Huijin Wei   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Current research in biotechnology: Exploring the biotech forefront

open access: yesCurrent Research in Biotechnology, 2019
Biotechnology is an evolving research field that covers a broad range of topics. Here we aimed to evaluate the latest research literature, to identify prominent research themes, major contributors in terms of institutions, countries/regions, and journals.
Andy Wai Kan Yeung   +36 more
doaj   +1 more source

Den groteske JegerenEstetikkens samfunnsrelevans i Per Dybvigs Jegeren: En fortelling fra skogen

open access: yesKunst og Kultur, 2023
Jegeren: En fortelling fra skogen (2015) av Per Dybvig er ei bildebok og kunstbok som viser gnager-lignende dyr med overraskende utvekster på kroppen. Grotesk estetikk og ulike typer hybriditet er gjennomgående i verket, samt bildekomponenter som innbyr ...
Helge Ridderstrøm
doaj   +1 more source

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