Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Environmental Biotechnology Research Group: Research Report. [PDF]
Environmental biotechnology exploits living organisms (plant, bacteria, fungi, etc) in various applications of waste treatment and remediation of pollutants.
Faculty of Biotechnology & Biomolecular Sciences, Environmental Biotechnology Research Group
core
The role of government in developing the biotechnology industry: a South African perspective
Biotechnology has been identified as one of the key sectors for future economic growth in many countries, with South Africa being no exception. Consequently, the South African government introduced the National Biotechnology Strategy (NBS) in 2001 to ...
Ramazan Uctu, Hassan Essop
doaj +1 more source
Deep mutational scanning: A versatile tool in systematically mapping genotypes to phenotypes
Unveiling how genetic variations lead to phenotypic variations is one of the key questions in evolutionary biology, genetics, and biomedical research.
Huijin Wei +4 more
doaj +1 more source
International ...
Guis, M. +4 more
openaire +2 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Den groteske Jegeren
Jegeren: En fortelling fra skogen (2015) av Per Dybvig er ei bildebok og kunstbok som viser gnager-lignende dyr med overraskende utvekster på kroppen. Grotesk estetikk og ulike typer hybriditet er gjennomgående i verket, samt bildekomponenter som innbyr ...
Helge Ridderstrøm
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Perceptions of emerging biotechnologies
Research on public views of biotechnology has centered on genetically modified (GM) foods. However, as the breadth of biotechnology applications grows, a better understanding of public concerns about non-agricultural biotechnology products is needed in ...
Christina B Azodi, Thomas Dietz
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source

