Results 41 to 50 of about 13,826 (180)

Modulation of host cell pathways by Coxiella burnetii Dot/Icm effectors

open access: yesmLife, Volume 4, Issue 6, Page 577-596, December 2025.
Abstract Coxiella burnetii, the etiological agent of Q fever, is a significant intracellular bacterial pathogen. C. burnetii is a highly infectious pathogen that primarily targets pulmonary alveolar macrophages during natural infection. It can then disseminate to macrophages in other tissues and organs, leading to chronic infections. C.
Jingya Yuan   +3 more
wiley   +1 more source

Peptide nucleic acid biosensors: Structure–interface interactions, electrochemical signal strategies, and diagnostic applications

open access: yesVIEW, Volume 6, Issue 6, December 2025.
This review discusses the structural and functional properties of peptide nucleic acid (PNA)‐based biosensors, emphasizing their sensitivity, enzymatic resistance, and diagnostic potential. It presents a comparative analysis of detection limits across sensor designs, focusing on probe immobilization, electrode composition, and signal amplification. The
Younghwan Kim, Swomitra Kumar Mohanty
wiley   +1 more source

Survey on AI Ethics: A Socio‐Technical Perspective

open access: yesComputational Intelligence, Volume 41, Issue 6, December 2025.
Abstract The past decade has observed a significant advancement in AI, with deep learning‐based models being deployed in diverse scenarios, including safety‐critical applications. As these AI systems become deeply embedded in our societal infrastructure, the repercussions of their decisions and actions have significant consequences, making the ethical ...
Dave Mbiazi   +5 more
wiley   +1 more source

Evaluating Detection and Diagnostic Decision Support Systems for Bioterrorism Response

open access: yesEmerging Infectious Diseases, 2004
We evaluated the usefulness of detection systems and diagnostic decision support systems for bioterrorism response. We performed a systematic review by searching relevant databases (e.g., MEDLINE) and Web sites for reports of detection systems and ...
Dena M. Bravata   +6 more
doaj   +1 more source

Assessing global pandemic risks from emerging infectious diseases and high containment laboratory leaks: A country‐level spatial network SIR model analysis

open access: yesRisk Analysis, Volume 45, Issue 12, Page 4619-4643, December 2025.
Abstract Future pandemics could arise from several sources, notably, emerging infectious diseases (EID); and lab leaks from high containment biological laboratories (HCBL). Recent advances in infectious disease, information technology, and biotechnology provide building blocks to reduce pandemic risk if deployed intelligently.
Ross J. Tieman   +2 more
wiley   +1 more source

Assessment of Knowledge and Attitude of Dentists Toward Bioterrorism Awareness in Dhule (Maharashtra, India): A Cross-sectional Survey

open access: yesJournal of Indian Association of Public Health Dentistry, 2017
Introduction: Bioterrorism, as a major health problem, has received lots of attention in the recent years. It is the intentional use of microorganisms and toxins to produce disease and death in humans, livestock, and crops; their attraction in war and ...
Minal M Kshirsagar   +5 more
doaj   +1 more source

PROTOCOL: Interventions to Prevent Cognitive and Behavioural Violent Radicalisation: A Systematic Review and Multilevel Meta‐Analysis

open access: yesCampbell Systematic Reviews, Volume 21, Issue 3, September 2025.
ABSTRACT This is a protocol for a Campbell systematic review. This review aims to systematically evaluate the available evidence on the effectiveness of various interventions aimed at reducing violent radicalisation and terrorism. Quantitative analysis will be employed to assess the overall impact and identify the factors that influence it.
Sara Valdebenito, Manuel Eisner
wiley   +1 more source

Investigation Into the Effect of Vaccination on Pulmonary Involvements in Patients With COVID‐19 Infection, Based on High‐Resolution CT Imaging

open access: yesThe Clinical Respiratory Journal, Volume 19, Issue 9, September 2025.
Patients with COVID‐19 pneumonia: Vaccinated versus non‐vaccinated. ABSTRACT Background COVID‐19 infection has been a major pandemic of this century, causing deaths, economic hardship, and poverty worldwide. At the moment, vaccination remains the most effective measure against this health challenge.
Elahe Amani   +4 more
wiley   +1 more source

Botulinum Neurotoxins: History, Mechanism, and Applications. A Narrative Review

open access: yesJournal of Neurochemistry, Volume 169, Issue 8, August 2025.
Botulinum neurotoxins (BoNTs), produced by Clostridium botulinum, bind irreversibly to presynaptic cholinergic nerve terminals and exploit a zinc‐dependent mechanism to cleave SNARE proteins, blocking acetylcholine release and causing flaccid paralysis.
Arik Monash   +3 more
wiley   +1 more source

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