Results 111 to 120 of about 71,056 (300)
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer +7 more
wiley +1 more source
Perchlorate (ClO4 −) contamination in water poses global health risks, yet its efficient reduction to harmless Cl− under mild conditions remains challenging.
Hejie Qin +8 more
doaj +1 more source
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza +4 more
wiley +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz +4 more
wiley +1 more source
Bacteriophage survival and ARG dissemination from wastewater treatment plants to the environment
The proliferation of antibiotic resistance genes (ARGs) represents a critical global health threat, with wastewater treatment plants (WWTPs) identified as major hotspots for resistance amplification and dissemination. While bacterial conjugation has been
Syeda Fazoon Kazmi +4 more
doaj +1 more source
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Isolation and screening of soil microorganisms capable of biotransformation of ...
Marešová, Helena
core
Altered gene expression in the liver and small intestine of horses with equine neuroaxonal dystrophy
Abstract Background Equine neuroaxonal dystrophy/degenerative myeloencephalopathy (eNAD/EDM) is the second most common diagnosis of spinal ataxia in horses in the United States. The disease develops due to a combination of vitamin E deficiency and an unknown genetic risk factor(s), and there currently is no effective treatment.
Stephanie Ryan +4 more
wiley +1 more source
Biotransformation of anthelmintics in nematodes in relation to drug resistance
In all organisms, the biotransformation of xenobiotics to less toxic and more hydrophilic compounds represents an effective defense strategy. In pathogens, the biotransformation of drugs (used for their elimination from the host) may provide undesirable ...
Ondřej Vosála +7 more
doaj +1 more source

