Results 121 to 130 of about 8,785 (292)

Industrial multi-step biotransformations

, 2004
Biotransformations have moved far beyond the classic one-reaction approach. Progress in genomic science enables the rapid assembly of complex multi-enzyme catalysts that allow [i] utilizing cheaper starting materials, as in the case of 5-acetylneuraminic
Kümmel, A., Heinemann, M.; id_orcid, Panke, S., Schümperli, M.   +3 more
core   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Mycotoxin management in the cereal supply chain: Advanced detection, detoxification, and smart packaging strategies

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Mycotoxins remain a persistent threat to the safety and quality of cereal grains and other agricultural products, and their impact on human health continues to raise global concerns. In many situations, the practices traditionally used to control these toxins are no longer sufficiently effective. They can be costly, difficult to implement on a
Abolfazl Asqardokht‐Aliabadi, Dipendra Kumar Mahato, Jafar Mohammadzadeh Milani   +2 more
wiley   +1 more source

Sourdough fermentation as a modulator of nutritional quality in cereal‐based baked products

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Sourdough fermentation, an ancient food bioprocessing technology, has attracted renewed attention for its positive impact on the nutritional profile and sensory attributes of leavened baked products. This process relies on the symbiotic activity between lactic acid bacteria and yeasts, which leads to acidification, proteolysis, enzyme ...
Reyna Stefanson, Sathsara Deyalage, Sachini Senarathna, Maneka Malalgoda   +3 more
wiley   +1 more source

Multistep one-pot processes in aqueous media by combination of palladium-catalyzed cross-coupling reactions and biotransformations

, 2009
Burda E, Hummel W, Gröger H. Multistep one-pot processes in aqueous media by combination of palladium-catalyzed cross-coupling reactions and biotransformations. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY.
Gröger, Harald, Burda, Edyta, Hummel, Werner   +2 more
core  

Optimal‐Control 19F PROJECT Improves the Reliability of CPMG‐Derived Relaxation Rates

Magnetic Resonance in Chemistry, EarlyView.
PROJECT with seedless optimal control pulses for 19F‐based protein‐ligand interaction screenings allows for a lower error in R2 estimates than those obtained with CPMG for J‐coupled fluorine signals and is indistinguishable from CPMG when the coupling is negligible, at the price of a modest reduction in SNR.
Marco Schiavina, Enrico Luchinat, Enrico Ravera   +2 more
wiley   +1 more source

2‐Amino‐3H‐phenoxazin‐3‐one is a lead inhibitor of Cuscuta campestris early development: structure–activity relationships of o‐aminophenol‐derived allelochemicals

Pest Management Science, EarlyView.
Phenoxazinones caused differential types of phytotoxic effects in C. campestris early development. APO is a coherent lead inhibiting C. campestris germination and early seedling growth. Abstract BACKGROUND 2‐Amino‐3H‐phenoxazin‐3‐one (synonym: questiomycin A; abbreviated as APO or Phx‐3) is a naturally occurring phenoxazinone‐type allelochemical with ...
Cristina Díaz‐Franco, Mónica Fernández‐Aparicio, José MG Molinillo, Rosa M Varela, Francisco A Macías, Jesús G Zorrilla   +5 more
wiley   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 523-539, March 2025.
Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo, Woojin Jung, Tham Thi Bui, Hwi‐yeol Yun, Jung‐woo Chae, Jeremiah D. Momper   +5 more
wiley   +1 more source