Results 61 to 70 of about 78,578 (289)
Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node-Targeting and Augments mRNA Vaccine Efficacy. [PDF]
Adv Sci (Weinh)Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Ha M +5 more
europepmc +2 more sources
Hydroxylations of Biphenyl by Fungi [PDF]
Journal of Applied Bacteriology, 1980 Sixty‐six species of fungi were screened for their ability to hydroxylate biphenyl. Thin‐layer and gas chromatographic analyses indicated that seven organisms actively hydroxylated this substrate. Of particular interest were Cunninghamella echinulata ATCC 9244 which produced 4‐hydroxybiphenyl
R V, Smith +3 more
openaire +2 more sources
, 2007 We report on the pairing properties of oligodeoxynucleotides containing chemically functionalized biphenyl residues instead of natural nucleobases. The synthesis of the corresponding C-nucleosides with one or two nitro- or methoxy groups, resp.
Leumann, Christian J., Zahn, Alain
core +2 more sources
Organic Materials of Tomorrow: Horizons of Artificial Intelligence
Advanced Materials, EarlyView.This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena +3 more
wiley +1 more source
, 2016 The synthesis of a series of meso-5,15-diphenylporphyrins strapped by 2,2‘-disubstituted biphenyl units (6H2, 7H2, 8H2) is described. The biphenyl straps used are linked via their 3,3‘-positions by CH2O groups to ortho-positions of the phenyl rings of ...
Jean Fischer (2963988) +3 more
core +2 more sources
Research Results in PharmacologyIntroduction: Based on the chemical structures of known Rho-kinase-2 inhibitors, 18 benzimidazole derivatives were synthesized and studied for their ophthalmic hypotensive activity in animals with normal intraocular pressure.
Olga N. Zhukovskaya +6 more
doaj +1 more source
High Birefringence Liquid Crystals
Crystals, 2013 Liquid crystals, compounds and mixtures with positive dielectric anisotropies are reviewed. The mesogenic properties and physical chemical properties (viscosity, birefringence, refractive indices, dielectric anisotropy and elastic constants) of compounds
Jakub Herman +2 more
doaj +1 more source
Adsorption‐Engineered Hydrocarbon Ionomers for Durable Proton‐Exchange Membrane Fuel Cells
Advanced Materials, EarlyView.Hydrocarbon ionomers suffer from oxidation‐driven interfacial degradation in PEM fuel cell cathodes, leading to catalyst instability. Here, adsorption‐engineered poly(fluorene) ionomers decouple interfacial anchoring from oxidative degradation, enabling strong catalyst–ionomer interactions while resisting electrochemical oxidation.
Heemin Park +14 more
wiley +1 more source
NanomaterialsIn this study, two novel hybrid monomers (4BD-EDOT and 3BD-EDOT) containing a biphenyl group and a 3,4-ethylenedioxythiophene (EDOT) unit were synthesized and polymerized electrochemically in a CH2Cl2-Bu4NPF6 electrolyte solution.
Shuanglai Shen +4 more
doaj +1 more source
Conductance through single biphenyl molecules: symmetric and asymmetric coupling to electrodes
Beilstein Journal of Nanotechnology, 2015 The contacts and the chemical bonds formed between metallic electrodes and molecules determine to a large extent the conductive properties of single molecular junctions, which represent the smallest possible active elements in an electronic circuit.
Karthiga Kanthasamy, Herbert Pfnür
doaj +1 more source