Results 141 to 150 of about 387,451 (287)
Mathematical Modeling of Risk-Taking in Bipolar Disorder: Evidence of Reduced Behavioral Consistency, With Altered Loss Aversion Specific to Those With History of Substance Use Disorder [PDF]
, 2022 Carly A Lasagna +5 more
openalex +1 more source
Advanced Science, EarlyView.A tri‐component biomimetic bioink(gelatin/alginate/fibrinogen) is developed to protect cells in critical pathological environments in AD. Using this bioink, a 3D‐printed NPC construct optimized for hippocampal transplantation is provided to improve cell retention and differentiation in an AD‐like model. This approach enhances memory recovery and offers
Ke Gai +12 more
wiley +1 more source
Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming
Advanced Science, EarlyView.Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu +13 more
wiley +1 more source
Atypical antipsychotics are associated with incident diabetes in older adults without schizophrenia or bipolar disorder [PDF]
, 2012 Neelam Thakurathi, David C. Henderson
openalex +1 more source
Advanced Science, EarlyView.The Phospholamban (PLN) R9C mutation reduces SERCA2a binding, increasing calcium recycling and baseline contractility. However, the excess of free PLN promotes pentamer formation, limiting phosphorylation and blunting β‐adrenergic signaling. Under cardiac stress, enhanced functional demands overwhelm proteostasis in PLN R9C cells, leading to misfolded ...
Qi Yu +10 more
wiley +1 more source
Widespread white matter tract aberrations in youth with familial risk for bipolar disorder
, 2015 Donna Roybal +6 more
openalex +2 more sources
Parabiosis, Assembloids, Organoids (PAO)
Advanced Science, EarlyView.This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong +5 more
wiley +1 more source
Advanced Science, EarlyView.Li‐ and V‐intercalated V2Se2O bilayers possess intralayer ferrimagnetic and interlayer ferromagnetic orders, alongside ferroelasticity, in‐plane uniaxial magnetic anisotropy, half‐metal/enhanced spin splitting, the anomalous Hall effect, giant magnetoresistance, tunneling magnetoresistance, near‐perfect spin filtering effect, spin Seebeck effect, and ...
Long Zhang +7 more
wiley +1 more source