Results 151 to 160 of about 3,359,821 (389)
Bipolar Disorder and Diabetes Mellitus [PDF]
, 2010 Comorbid endocrine and cardiovascular situations with bipolar disorder usually result from the bipolar disorder itself or as a consequence of its treatment.
A. Gorkem Gençer, Sermin Kesebir
core
Long Term High‐Salt Diet Induces Cognitive Impairments via Down‐Regulating SHANK1
Advanced Science, EarlyView.The study identifies a novel mechanistic link between long‐term HS diet and cognitive impairment, wherein PKA/CREB axis inactivation leads to SHANK1 reduction, synaptic damage, and cognitive deficits. Abstract High‐salt (HS) diet is an established risk factor for cognitive impairment, but the underlying mechanisms remain unclear.
Cuiping Guo +10 more
wiley +1 more source
Multi‐Region Brain Organoids Integrating Cerebral, Mid‐Hindbrain, and Endothelial Systems
Advanced Science, EarlyView.Multi‐Region Brain Organoids combine cerebral, mid/hindbrain, and endothelial components into an advanced 3D model capturing 80% of fetal brain cellular diversity. This platform reveals essential endothelial‐neural signaling networks that maintain region‐specific intermediate progenitors during hindbrain development.
Anannya Kshirsagar +10 more
wiley +1 more source
The Mood Disorder Questionnaire improves recognition of bipolar disorder in psychiatric care
BMC Psychiatry, 2003 Background We investigated our translation of The Mood Disorder Questionnaire (MDQ) as a screening instrument for bipolar disorder in a psychiatric setting in Finland.
Leppämäki Sami +6 more
doaj +1 more source
Advanced Science, EarlyView.Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge +7 more
wiley +1 more source
PLoS ONE, 2013 Bipolar disorder is a severe mental illness characterized by recurrent manic and depressive episodes. In bipolar disorder, family and twin studies suggest contributions from genetic and environmental factors; however, the detailed molecular pathogenesis ...
An-a Kazuno +6 more
doaj +1 more source
Two novel variants in the DOPA decarboxylase gene: association with bipolar affective disorder [PDF]
, 1999 Anders D. Børglum +9 more
openalex +1 more source
Adult Bipolar Disorder is Continuous with Pediatric Bipolar Disorder [PDF]
The Canadian Journal of Psychiatry, 2007 Considerable debate exists regarding the continuity of bipolar disorder (BD) in children and adolescents. Do affected children continue to have BD as adults? Are pediatric forms of BD distinct from adult forms of the disorder? Here, I argue that, in fact, strictly defined BD I and II in children and adolescents is continuous with adult BD.
openaire +3 more sources
Advanced Science, EarlyView.Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu +7 more
wiley +1 more source