Results 151 to 160 of about 3,398,277 (373)

Mutational analysis of phospholipase A2A: a positional candidate susceptibility gene for bipolar disorder [PDF]

, 1999
Nick Jacobsen, Emily Franks, M J Owen, Nick Craddock   +3 more
openalex   +1 more source

Single‐Cell Transcriptome Analysis Reveals That Hmga2 Regulates Neuroinflammation and Retinal Function by Modulating Müller Cell Autophagy Through PI3K/AKT Signaling Following MCAO‐Induced Retinal Ischemia

Advanced Science, EarlyView.
Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv, Juzheng Yuan, Zhe Ruan, Ya‐nan Dou, Hongchen Zhang, Xiaowei Fei, Leiying Chen, Zehan Zhang, Kai Yang, Xiuquan Wu, Zhou Fei, Fei Fei   +11 more
wiley   +1 more source

The Critical Role of Enhanced OXPHOS and Mitochondrial Hyperpolarization in Simulated Microgravity‐Induced Oocyte Maturation Arrest

Advanced Science, EarlyView.
Simulated microgravity induces distinct mitochondrial hyperactivation patterns‐elevated OXPHOS and MMP‐which accelerate meiosis without SAC failure but delays MTOC coalescence, leading to spindle defects and meiotic arrest. Prolonging M‐phase restores MTOC assembly and oocyte maturation.
Lei Ge, Yuqing Gao, Feifei Du, Chiyuan Ma, Tianxia Xiao, Yali Yang, Xiaohua Lei, Jian V. Zhang   +7 more
wiley   +1 more source

Gabapentin in bipolar disorder [PDF]

, 1997

openalex   +1 more source

Bipolar Disorder

Skin & Allergy News, 2006
Otto, M, Miklowitz, D
  +6 more sources

Genetic Evidence Supporting a Role for Brain Region Volume and Functional Network Alterations in Major Depression

Advanced Science, EarlyView.
Genome‐wide analyses indicate that reduced ventral diencephalon and thalamus volumes, along with decreased functional connectivity within the triple network (DMN/CEN/SN), are uniquely associated with the risk of major depression (MD) onset, compared to other similar severe psychiatric disorders.
Ming‐Min Xu, Nan Li, Yi‐Wen Lv, Wen‐Miao Yang, Zhi‐Yun Yu, Yi‐Min Zhang, Yu Guo, Xiao‐Yin Chen   +7 more
wiley   +1 more source

Local p‐ and n‐Type Doping of an Oxide Semiconductor via Electric‐Field‐Driven Defect Migration

Advanced Science, EarlyView.
Local acceptor and donor doping is achieved in a semiconducting oxide by controlled splitting of oxygen interstitial‐vacancy pairs under applied d.c. voltage. The separated oxygen defects are demonstrated to form interstitial‐rich (p‐type) and vacancy‐rich (n‐type) regions, comparable to dipolar npn‐junctions, enabling transient functionalization ...
Jiali He, Ursula Ludacka, Kasper A. Hunnestad, Didrik R. Småbråten, Konstantin Shapovalov, Per Erik Vullum, Constantinos Hatzoglou, Donald M. Evans, Erik D. Roede, Zewu Yan, Edith Bourret, Sverre M. Selbach, David Gao, Jaakko Akola, Dennis Meier   +14 more
wiley   +1 more source

Analysis of a novel functional polymorphism within the promoter region of the serotonin transporter gene (5-HTT) in Brazilian patients affected by bipolar disorder and schizophrenia [PDF]

, 1998
Jo�o R. Mendes de Oliveira, Paulo Alberto Otto, Homero Vallada, V. Lauriano, Hélio Elkis, Beny Lafer, Luciana Vasquez, Valentim Gentil, Maria Rita Passos‐Bueno, Mayana Zatz   +9 more
openalex   +1 more source

Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis

Advanced Science, EarlyView.
Meiosis is a specialized form of cell division that has different regulation and mechanisms with mitosis in numerous aspects. Particularly, meiosis I is unique and occurs only in germ cells to separate homologous chromosomes. Thus, determining how this unusual chromosome segregation behavior is established is central to understanding germ cell ...
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
wiley   +1 more source

The genetic association between bipolar disorder and dementia: a qualitative review

Frontiers in Psychiatry
Bipolar disorder is a chronic disorder characterized by fluctuations in mood state and energy and recurrent episodes of mania/hypomania and depression. Bipolar disorder may be regarded as a neuro-progressive disorder in which repeated mood episodes may ...
Hirofumi Hirakawa, Takeshi Terao
doaj   +1 more source