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New England Journal of Medicine, 2020
Mood fluctuations are common during normal daily life as a result of either stressful or pleasant events. However, severe and persistent mood swings that result in psychological distress and behavioural impairment may be symptomatic of an underlying affective disorder.
Sergio A, Strejilevich +2 more
openaire +5 more sources
Mood fluctuations are common during normal daily life as a result of either stressful or pleasant events. However, severe and persistent mood swings that result in psychological distress and behavioural impairment may be symptomatic of an underlying affective disorder.
Sergio A, Strejilevich +2 more
openaire +5 more sources
Current Opinion in Neurobiology, 2023
This review focuses on recent advances made towards understanding the neurobiology of bipolar disorder (BD), a chronic neuropsychiatric illness characterized by altered mood and energy states. The past few years have seen the completion of the largest genetic studies by far, which have emphasized the polygenic nature of BD as well as it's connection to
Madeline R. Scott, Colleen A. McClung
openaire +2 more sources
This review focuses on recent advances made towards understanding the neurobiology of bipolar disorder (BD), a chronic neuropsychiatric illness characterized by altered mood and energy states. The past few years have seen the completion of the largest genetic studies by far, which have emphasized the polygenic nature of BD as well as it's connection to
Madeline R. Scott, Colleen A. McClung
openaire +2 more sources
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4 [PDF]
Nature Genetics, 2011 We conducted a combined genome-wide association study (GWAS) of 7,481 individuals with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS Consortium.
Martin Schalling +2 more
exaly +3 more sources
Mental Health Services Research, 2002
Manic-depressive (bipolar) disorder is a severe, relapsing mental illness that shares characterstics both with major depressive disorder and with serious mental illnesses such as schizophrenia. Like schizophrenia, it is a chronic disorder, and is treated primarily in the specialty mental health sector. Rates of appropriate treatment are low. Functional
Mark, Bauer +3 more
openaire +4 more sources
Manic-depressive (bipolar) disorder is a severe, relapsing mental illness that shares characterstics both with major depressive disorder and with serious mental illnesses such as schizophrenia. Like schizophrenia, it is a chronic disorder, and is treated primarily in the specialty mental health sector. Rates of appropriate treatment are low. Functional
Mark, Bauer +3 more
openaire +4 more sources
The Lancet, 2020
Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder, defined by the presence of a syndromal, hypomanic episode and a major depressive episode.
McIntyre, Roger S. +13 more
openaire +3 more sources
Bipolar disorders are a complex group of severe and chronic disorders that includes bipolar I disorder, defined by the presence of a syndromal, manic episode, and bipolar II disorder, defined by the presence of a syndromal, hypomanic episode and a major depressive episode.
McIntyre, Roger S. +13 more
openaire +3 more sources
The Lancet, 2016
Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state and energy. It affects more than 1% of the world's population irrespective of nationality, ethnic origin, or socioeconomic status. Bipolar disorder is one of the main causes of disability among young people, leading to cognitive and functional impairment and ...
Iria, Grande +3 more
openaire +4 more sources
Bipolar disorder is a recurrent chronic disorder characterised by fluctuations in mood state and energy. It affects more than 1% of the world's population irrespective of nationality, ethnic origin, or socioeconomic status. Bipolar disorder is one of the main causes of disability among young people, leading to cognitive and functional impairment and ...
Iria, Grande +3 more
openaire +4 more sources