Results 241 to 250 of about 194,956 (304)

Serum NfL, GFAP, and p‐tau217 in adults with drug‐resistant epilepsy and intellectual disabilities: Signs of ongoing neural injury

Epilepsia, EarlyView.
Abstract Objective Adults with epilepsy and intellectual disabilities (IDs) may be at increased risk of dementia, but clinical evaluation is complex and use of conventional biomarkers is often considered too invasive. We explored abnormality of serum neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and phosphorylated tau‐217 (p ...
Hadassa Kwetsie, Inge M. W. Verberk, Jans S. van Ool, Anneke J. J. Rampen, Rebecca Z. Rousset, Nicole I. Wolf, Dederieke A. M. Maes‐Festen, Clara D. M. van Karnebeek, Charlotte E. Teunissen, Erik Boot, Agnies M. van Eeghen   +10 more
wiley   +1 more source

Pediatric sensorimotor cortical responsiveness to intracerebral stimulation during stereoelectroencephalographic monitoring: Age effects and area specificity

Epilepsia, EarlyView.
Abstract Objective This study was undertaken to determine how age influences clinical responsiveness to intracerebral electrical stimulation (IES) in children across primary and secondary sensorimotor cortices and to assess age effects on response complexity and area‐specific responsiveness.
Giulia Nobile, Laura Tassi, Marta Ponzano, Piergiorgio d'Orio, Alessandro Consales, Luca Bosisio, Stefano Francione, Gabriele Arnulfo, Maria Pia Sormani, Lino Nobili, Roberto Mai   +10 more
wiley   +1 more source

Acid accumulation in bipolar disorder. [PDF]

J Affect Disord
Trevino-Alvarez AM, Pazdernik V, Gardea-Resendez M, Coombes BJ, Sanchez-Ruiz J, Ercis M, Singh B, Veldic M, Ozerdem A, McElroy SL, Romo-Nava F, Biernacka JM, Correa da Costa S, Cuellar-Barboza AB, Isazade V, Van Ligten MJ, Knapp JL, Holzman A, Yehia A, Frye MA, Abulseoud OA.   +20 more
europepmc   +1 more source

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

High‐frequency oscillations after acute hemorrhagic traumatic brain injury: insights into posttraumatic epilepsy development

Epilepsia, EarlyView.
Abstract Objective The development of posttraumatic epilepsy after traumatic brain injury (TBI) is potentially identifiable by measuring biomarkers of epileptogenesis, namely pathological high‐frequency oscillations (pHFOs). pHFOs are promising candidates, but it remains uncertain whether they can be detected early after TBI in clinical settings.
Kseniia Kriukova, Lin Li, Richard J. Staba, Misque Boswell, Tuba Asifriyaz, Rachel Thomas, James J. Gugger, Mohamad Shamas, Ramon Diaz‐Arrastia, Manuel Buitrago Blanco, Jerome Engel, Paul M. Vespa, Dominique Duncan, on behalf of the EpiBios4Rx investigators, Denes Agoston, Alicia K. Au, Michael Bell, Ben Churn, Jan Claassen, Ramon Diaz‐Arrastia, Jerome Engel, Brandon Foreman, Aristea Galanopoulou, Emily Gilmore, Martin Hunn, Nathalie Jette, Andrew Morokoff, Solomon L. Moshé, Terence O'Brien, Joshua Laing, Piero Perucca, Kristine H. O'Phelan, Asla Pitkanen, Eric Rosenthal, Frederick Willyerd, Lara Zimmermann, Ben Ellingson, Buitrago Blanco, Daniel Correa, Dana Harrar, Thomas P. Bleck, Brian Appavu, Aaron Struck, Baxter Allen, Inna Keselman, Jeff Kennedy, Victor Ferastraoaru, Ji Yeoun Yoo, Arthur W. Toga   +48 more
wiley   +1 more source

Elevated C-reactive protein is associated with suicide attempts in youth with bipolar disorder. [PDF]

Psychol Med
Desai D, Dimick MK, Kennedy KG, Sultan AA, Mio M, Goldstein BI.   +5 more
europepmc   +1 more source

Epilepsia partialis continua as the presenting manifestation of Creutzfeldt–Jakob disease: A video‐polygraphic clinical vignette

Epileptic Disorders, EarlyView.
Roberta Cutellè, Angelo Pascarella, Ada Santoro, Vittoria Cianci, Anna Mammì, Giovanbattista Gaspare Tripodi, Caterina Prestandrea, Sara Gasparini, Edoardo Ferlazzo   +8 more
wiley   +1 more source

Stereo‐EEG mapping of visual working memory with task‐related high‐gamma modulations

Epilepsia, EarlyView.
Abstract Objective We describe a safe, informative, and easy‐to‐implement approach for presurgical mapping of visual working memory (VWM) with stereo‐electroencephalography (SEEG). Methods Twenty‐four patients with drug‐resistant epilepsy, 11–23 years of age, performed a single‐probe change detection VWM task, during SEEG monitoring.
Brian Ervin, Jason Buroker, Taylor Cummins, Anna W. Byars, Craig Scholle, Leonid Rozhkov, Paul S. Horn, Jeffrey R. Tenney, Hansel M. Greiner, James L. Leach, Jesse Skoch, Francesco T. Mangano, Katherine D. Holland, Ravindra Arya   +13 more
wiley   +1 more source

Sleep characteristics and cognitive impairment in bipolar disorder: age-specific associations. [PDF]

Front Psychiatry
Martínez-Cuenca A, Moya-Lacasa C, García-Sánchez A, Couce-Sánchez M, Romero-Jiménez S, Sáiz PA, García-Portilla MP, González-Blanco L.   +7 more
europepmc   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source