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Bipolar disorder

The Lancet, 2002
Bipolar, or manic-depressive, disorder is a frequent, severe, mostly recurrent mood disorder associated with great morbidity. The lifetime prevalence of bipolar disorder is 1.3 to 1.6%. The mortality rate of the disease is two to three times higher than that of the general population.
Bruno, Müller-Oerlinghausen   +2 more
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Bipolar disorder

Nursing Standard, 2014
Essential facts. Bipolar disorder is a potentially lifelong and disabling condition. Bipolar I, characterised by episodes of mania and depression, is estimated to affect 1 per cent of the adult population. Bipolar II, characterised by hypomania and depression, affects an estimated 0.4 per cent of adults. Episodes can vary in length and frequency.
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Bipolar Disorder

2007
This chapter covers the treatment of bipolar disorder using an adaptation of IPT called Interpersonal and Social Rhythm Therapy (IPSRT). An amalgam of IPT with behavioral therapy developed by Frank and colleagues, IPSRT is an efficacious adjunct to medication for patients with bipolar I disorder.
Myrna M. Weissman   +2 more
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Bipolar disorder

New Directions for Mental Health Services, 1992
AbstractThe etiology of bipolar disorder (BD) has a complex genetic component; juvenile‐ and adolescent‐onset BD may be expressing the most genotypically severe form of the illness.
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Pharmacogenomics of Bipolar Disorder

Pharmacogenomics, 2013
Bipolar disorder (BD) is a lifelong severe psychiatric condition with high morbidity, disability and excess mortality. The longitudinal clinical trajectory of BD is significantly modified by pharmacological treatment(s), both in acute and in long-term stages.
Marta Costa   +9 more
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Anticonvulsants in bipolar disorder

Australian and New Zealand Journal of Psychiatry, 2006
Objective: To review the literature on the effectiveness of anticonvulsant drugs in the management of bipolar disorder. Methods: A selective review of the literature. Results: Valproate is an effective drug, alone or in combination, for mania, but has limited benefit in bipolar depression.
Charles L. Bowden, Nancy U. Karren
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Bipolar Disorder

2008
Abstract: Bipolar disorder, defined on the basis of manic symptoms, is one of the most severe psychiatric disorders. The disorder presents unique challenges to diagnosis, treatment, and prediction of outcome. Strong assessment tools can aid in making an appropriate diagnosis, identifying predictors of treatment response, and tracking the efficacy of ...
Sheri L. Johnson   +2 more
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Bipolar Disorders

2015
The overdiagnosis of bipolar disorders is one of the most troubling problems affecting contemporary practice. The concept of a bipolar spectrum has led to unnecessary pharmacological interventions in patients who do not have the classical symptoms of bipolarity.
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Suicide and Bipolar Disorder

Annals of the New York Academy of Sciences, 1986
Suicide, which is both a stereotypic yet highly individualized act, is a common endpoint for many patients with severe psychiatric illness. The mood disorders (depression and bipolar manic-depression) are by far the most common psychiatric conditions associated with suicide.
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Neuropsychology of Bipolar Disorder

2020
Bipolar disorder is associated with significant dysfunction in a broad range of neuropsychological domains and processes. Deficits have been reported to occur in symptomatic states (depression, [hypo]mania) as well as in remission (euthymia), having consequences for psychological well-being and social and occupational functioning.
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