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Bipolar disorder

Nursing Standard, 2014
Essential facts. Bipolar disorder is a potentially lifelong and disabling condition. Bipolar I, characterised by episodes of mania and depression, is estimated to affect 1 per cent of the adult population. Bipolar II, characterised by hypomania and depression, affects an estimated 0.4 per cent of adults. Episodes can vary in length and frequency.
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Bipolar Disorder

2007
This chapter covers the treatment of bipolar disorder using an adaptation of IPT called Interpersonal and Social Rhythm Therapy (IPSRT). An amalgam of IPT with behavioral therapy developed by Frank and colleagues, IPSRT is an efficacious adjunct to medication for patients with bipolar I disorder.
Myrna M. Weissman   +2 more
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Bipolar disorder

New Directions for Mental Health Services, 1992
AbstractThe etiology of bipolar disorder (BD) has a complex genetic component; juvenile‐ and adolescent‐onset BD may be expressing the most genotypically severe form of the illness.
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Pharmacogenomics of Bipolar Disorder

Pharmacogenomics, 2013
Bipolar disorder (BD) is a lifelong severe psychiatric condition with high morbidity, disability and excess mortality. The longitudinal clinical trajectory of BD is significantly modified by pharmacological treatment(s), both in acute and in long-term stages.
Marta Costa   +9 more
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Anticonvulsants in bipolar disorder

Australian and New Zealand Journal of Psychiatry, 2006
Objective: To review the literature on the effectiveness of anticonvulsant drugs in the management of bipolar disorder. Methods: A selective review of the literature. Results: Valproate is an effective drug, alone or in combination, for mania, but has limited benefit in bipolar depression.
Charles L. Bowden, Nancy U. Karren
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Cross-national epidemiology of major depression and bipolar disorder.

Journal of the American Medical Association (JAMA), 1996
OBJECTIVE To estimate the rates and patterns of major depression and bipolar disorder based on cross-national epidemiologic surveys. DESIGN AND SETTING Population-based epidemiologic studies using similar methods from 10 countries: the United States ...
M. Weissman   +16 more
semanticscholar   +1 more source

Bipolar Disorder

2008
Abstract: Bipolar disorder, defined on the basis of manic symptoms, is one of the most severe psychiatric disorders. The disorder presents unique challenges to diagnosis, treatment, and prediction of outcome. Strong assessment tools can aid in making an appropriate diagnosis, identifying predictors of treatment response, and tracking the efficacy of ...
Sheri L. Johnson   +2 more
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Bipolar Disorder and Suicide: a Review

Current Psychiatry Reports, 2020
Jacob N. Miller, D. Black
semanticscholar   +1 more source

Neuroserpin in Bipolar Disorder

Current Topics in Medicinal Chemistry, 2020
Objective: Neuroserpin is a serine protease inhibitor predominantly expressed in the nervous system functioning mainly in neuronal migration and axonal growth. Neuroprotective effects of neuroserpin were shown in animal models of stroke, brain, and spinal cord injury.
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Suicide and Bipolar Disorder

Annals of the New York Academy of Sciences, 1986
Suicide, which is both a stereotypic yet highly individualized act, is a common endpoint for many patients with severe psychiatric illness. The mood disorders (depression and bipolar manic-depression) are by far the most common psychiatric conditions associated with suicide.
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