Results 141 to 150 of about 2,893,142 (314)
Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis
ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit +10 more
wiley +1 more source
Background Flooding is a recurrent and worsening public health threat in Indonesia, disproportionately affecting women and children in low-elevation urban areas.
Riya Goel +10 more
doaj +1 more source
Childhood Poverty and Labour Market Exclusion. Findings from a Swedish Birth Cohort. [PDF]
Research has consistently shown that poverty and economic hardship have negative consequences for children. Few studies, however, have examined whether these consequences persists into adulthood.
Nilsson, Anders, Bäckman, Olof
core
ABSTRACT Objective To compare the incidence of diabetes mellitus and its associations with hospitalisation and mortality in adults with multiple sclerosis (MS) and matched controls. Methods Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 ...
Yolanda Lau +8 more
wiley +1 more source
Size at birth: an examination of meaning and usefulness. A prospective study of a cohort of infants born in Nepal [PDF]
Background: Low birth weight (LBW) remains a major public health problem in developing countries, but is only one measure of size at birth. Others include small-for-gestational-age (SGA) and low ponderal index (PI).
Vaidya, A.
core
Juvenile Huntington Disease With Cerebellar‐Predominant Atrophy Identified by Genome Sequencing
ABSTRACT Juvenile Huntington disease accounts for a small fraction of Huntington disease cases and is driven by the largest trinucleotide repeat expansions. We describe a 6‐year‐old boy with progressive global regression, generalized dystonia, and epilepsy, in whom serial imaging showed striking cerebellar‐predominant atrophy with an initially normal ...
Enrique Gonzalez Saez‐Diez +5 more
wiley +1 more source
ABSTRACT Background Biallelic FIG4 variants classically cause distinct conditions characterized by peripheral neuropathy (Charcot‐Marie‐Tooth disease type 4J) or skeletal dysplasia (Yunis‐Varón syndrome). However, central nervous system involvement is increasingly recognized. The prevalence and specific characteristics of movement disorders within FIG4‐
Andrea Gangfuß +22 more
wiley +1 more source
Birth Weight and the Dynamics of Early Cognitive and Behavioural Development [PDF]
In this paper we explore the impact of birth weight on children's cognitive and behavioural outcomes using data from the UK Millennium Cohort Study. In order to deal with the endogeneity of birth weight we use an estimator based on the eliminant method ...
Del Bono, Emilia, Ermisch, John
core
Myostatin/Smad3 in Spinal Muscular Atrophy: Biomarkers of Disease Severity and Treatment Response
ABSTRACT Objective Given the role of Myostatin (MSTN) in muscle homeostasis and its modulation by current spinal muscular atrophy (SMA) therapies, we investigated serum MSTN and, for the first time, its downstream effector Smad3 as candidate non‐invasive biomarkers in SMA patients undergoing disease‐modifying therapies (DMTs).
Giorgia Riolo +11 more
wiley +1 more source

