Results 191 to 200 of about 63,681 (258)

Incidence and risk factors of clavicle, humerus fractures, and brachial plexus injuries due to birth trauma in the neonatal period. [PDF]

Turk J Phys Med Rehabil
Surel F, Bilir EE, Elbaşı D, Şahingöz Bakırcı E, Canpolat FE, Adıgüzel E.   +5 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Management of Pediatric Hand Injuries in the Acute Setting Part 1: Principles of Pediatric Hand Surgery Management. [PDF]

J Pediatr Soc North Am
Sinclair MK, Santana D, Manske MC.
europepmc   +1 more source

Kaempferol Attenuates Spaceflight‐Associated Knee Cartilage Degradation by Targeting NOX4‐Mediated Mitochondrial Dysfunction

Advanced Science, EarlyView.
We have shown that both simulated and actual spaceflight contribute to cartilage degradation in the knees of mice. Using RNA sequencing and bioenergetic profiling, we identified NADPH oxidase 4 (NOX4) as a key factor driving these changes. Additionally, we found that kaempferol, a naturally occurring flavonoid that binds directly to NOX4, reduces ...
Yuesong Yin, Ruiling Xu, Meagan J. Makarczyk, Jia‐Jun Liu, Silvia Liu, Matthew Z. Shi, Roberta Di Carlo, Michael F. Almeida, Alex Garris, Sarah Day, Rebekah Sanchez‐Hodge, Jonathan C. Schisler, Aleeza H. Zilberman, Noah G. Allen, Angela J. Kubik, Elizabeth A. Blaber, Arnold Z. Olali, Wanqing Xie, Douglas C. Wallace, Christopher E. Mason, Peter G. Alexander, Giuseppe Intini, Afshin Beheshti, Hang Lin   +23 more
wiley   +1 more source

The 30-year evolution of motor vehicle road injuries: Can the future come from the shadows? [PDF]

PLoS One
Zhao S, Lan Z, Lin J, Kan S, Jiao Y, Chen L, Du Y.   +6 more
europepmc   +1 more source

Targeting GALNT7 Disrupts the TAZ O‐GalNAcylation Feedback Loop to Suppress Gallbladder Cancer Progression

Advanced Science, EarlyView.
Aberrant GALNT7‐mediated O‐GalNAcylation stabilizes TAZ to drive gallbladder cancer progression through a feed‐forward transcriptional loop. Structure‐based screening identifies Olaparib as a potent GALNT7 antagonist that disrupts this oncogenic axis, providing an immediate therapeutic strategy for this aggressive malignancy.
Peng Qiu, Ming Zhang, Yunxiang Feng, Yibo Deng, Kai Zhao, Xiangyu Li, Yun Lu, Li Tian, Tao Yang, Wei Yao, Jianming Wang, Zhengdong Deng   +11 more
wiley   +1 more source

The Use of Transperineal and Endoanal Ultrasound in Diagnosis and Management of Obstetric Anal Sphincter Injuries (OASIs): A Narrative Review from a Gynecologic Perspective. [PDF]

Diagnostics (Basel)
Pagkaki C, Papasozomenou P, Oikonomou E, Stavros S, Potiris A, Koutlaki N, Zafrakas M, Gerede A.   +7 more
europepmc   +1 more source

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Fetal parietal bone fracture in late 3rd trimester secondary to traffic accident with improper seatbelt use: a case report. [PDF]

Arch Gynecol Obstet
Demir FN, Koyun M, Kayıkçı U.
europepmc   +1 more source

Prevalence and Predictors of Severe Perineal Tears Following Episiotomy: A Cross-Sectional Study in Uganda. [PDF]

Int J Womens Health
Akampurira G, Tumwesigye R, Ainomugisha B, Kayondo M.   +3 more
europepmc   +1 more source