Results 221 to 230 of about 2,802,204 (341)

Testing Higher Doses of Sildenafil to Repair Brain Injury Secondary to Birth Asphyxia: An Open-Label Dose-Finding Phase 1b Clinical Trial–Sildenafil Administration to Treat Neonatal Encephalopathy–Study 02

Pia Wintermark, Anie Lapointe, Gabriel Altit, Robin H. Steinhorn, Emmanouil Rampakakis, Andreas D. Meid, Jürgen Burhenne, Gzona Bajraktari‐Sylejmani, May Khairy, Marie-Therese Adamo, Guillaume Gilbert, Daniela Toffoli, Samara Zavalkoff, Thuy Mai Luu, Elizabeth Hailu, Walter E. Haefeli   +15 more
openalex   +2 more sources

Metabolic Derangement in Birth Asphyxia due to Cellular Injury with Reference to Mineral Metabolism in Different Stages of Hypoxic-ischemic Encephalopathy in Central India

, 2017
Amrita Vamne, Bhawna Bhimte
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

Impact of maternal age on the risk of perineal injury and obstetric anal sphincter injury in nulliparous women. [PDF]

Arch Gynecol Obstet
Attali E, Gabbai D, Gold R, Groutz A, Yogev Y, Baruch Y.   +5 more
europepmc   +1 more source

Experiences of Maternal Birth Injuries : How Gender and Sexuality Norms Affect Diagnostics, Everyday Life and Healthcare in Sweden

, 2018
Sara Persson
openalex   +1 more source

The association between waterbirth and perineal injury or other adverse outcomes among low-risk women with physiological birth: Results from the Nordic Home Birth Cohort Study

Berglind Hálfdánsdóttir, Karianne Ellinger-Kaya, Kathrine Fjøsne, Helena Lindgren, Hanne Kristine Hegaard, Ellen Blix   +5 more
openalex   +1 more source

The proportion of obstetric anal sphincter injuries and associated factors among mothers who gave birth vaginally at Habru Woreda public health institutions, Amhara region, Northeast, Ethiopia, 2022 [PDF]

Belyu Yehualashet Weldearegay, Simegnew Asmer Getie, Sewareg Mulu sewalem, Bizualem Tadesse Kemaw, Birhan Ambachew Taye   +4 more
openalex   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

Long‐Term Effects of Xenotransplantation of Human Enteric Glia in an Immunocompetent Rat Model of Acute Brain Injury

Advanced Science, EarlyView.
Acute brain injuries are characterized by extensive tissue damage, resulting in debilitating deficits in patients. Despite considerable progress, cell‐based approaches have yet to identify an ideal candidate. This long‐term study explores the use of an untested cell source – human enteric glia – and a non‐invasive administration route – intranasal ...
Nina Colitti, Edwige Rice, Franck Desmoulin, Maylis Combeau, Mélissa Parny, Lorenne Robert, Etienne Buscail, Barbara Bournet, Nathalie Vergnolle, Isabelle Raymond‐Letron, Isabelle Loubinoux, Carla Cirillo   +11 more
wiley   +1 more source