Results 21 to 30 of about 594,977 (260)

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

BIRTH RATE AND BIRTH RIGHT [PDF]

American Journal of Public Health and the Nations Health, 1963
cial science theory as well as psychodynamic theory to social work practice. The family-centered approach to practice is stressed as is the concern of the profession in seeking new ways of 'reaching the so-called multiproblem family. The articles deal with the expanding role of casework from its traditional relationship with the individual to work with
openaire   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Implementation of the K-Nearest Neighbor Algorithm for Birth Rate Prediction

Journal of Applied Informatics and Computing
This study aims to predict the monthly birth rate using the K-Nearest Neighbor (KNN) regression algorithm. The dataset consists of historical data from 2010 to 2020, covering six districts and including variables such as total population, number of ...
Akhyar Alhafiz, Rakhmat Kurniawan R.
doaj   +1 more source

Natural reduction of Ukraine’s population: Regional dimensions of the national threat

Hungarian Geographical Bulletin, 2021
A significant decline in Ukraine’s population is mainly due to its natural decrease, which began in the 1970s and 1980s in the rural areas and had been determined by the objective trends in demographic transition, the inertia effect of the demographic ...
Myroslav Dnistrianskyi, József Molnár, Iryna Chaika   +2 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Vital strategies as regulators of the demographic behavior of a family and a person [PDF]

Экономика региона, 2011
This paper reviews the problem of choosing some identified strategies for life by various population groups and the impact of this phenomenon on the regulation of mass demographic behavior.
Aleksandr Ivanovich Kuzmin, Tatyana Vladimirovna Primak, Anastasiya Aleksandrovna Kuzmina   +2 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Changes in seasonality of births in Poland in the years 1900-2009

Demographic Research, 2019
Background: To date, several countries have documented changes over time in the pattern of seasonal fluctuations of births. Differences in these changes between countries allow us to better understand the social and economic factors determining birth ...
Jacek Cypryjański
doaj   +1 more source