Results 71 to 80 of about 1,917,180 (294)

Demographic transition in South Korea: implications of falling birth rates [PDF]

open access: yesClinical and Experimental Pediatrics
This review examines the critical issues of declining total fertility rates (TFRs) and aging populations in East Asia with special focus on South Korea.
Chae Young Kim, Sung-Hoon Chung
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Iringa Regional and District Projections. [PDF]

open access: yes, 2006
This report presents population projections for the period 2003 to 2025 for Iringa Region and its districts. The projections were made using a Cohort Component Method (Spectrum System), whereby three components responsible for population change, namely ...
Aboud,, S. M.   +9 more
core  

Chlamydia trachomatis infection and the risk of perinatal mortality in Hungary [PDF]

open access: yes, 2001
Introduction: Chlamydial infections of the genital tract are thought to often lead to preterm birth, which is the most important perinatal problem in Hungary.
Ancel Y   +8 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Working Women and Motherhood: Failures of the Weimar Republic’s Family Policies

open access: yes, 2014
This paper examines the Weimar Republic’s reaction to the population crisis after the First World War. The Reich government created welfare policies to boost the birth rate and decrease the infant mortality rate.
Quirin, Katelyn M.
core  

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

THE POPULATION AGE STRUCTURE IN THE ARCTIC REGIONS OF THE REPUBLIC OF SAKHA (YAKUTIA): TRENDS AND DRIVERS OF CHANGE

open access: yesСевер и рынок: формирование экономического порядка
The demographic situation in the Arctic regions presents a complex and multifaceted challenge that constrains their potential for sustainable socio-economic development.
Valentina I. Kondratieva   +1 more
doaj   +1 more source

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