Results 141 to 150 of about 1,627,187 (248)
An Integrated DNA Nanoprobe for Intranuclear Imaging and in Situ Profiling of OGG1 Activity
The TP‐SA nanoprobe, integrating an AS1411 aptamer for nuclear delivery and a FRET array for signal amplification, enables real‐time tracking of nuclear OGG1 activity. It reveals cell‐line‐specific basal OGG1 levels and shows clinical promise using pneumonia patients’ lavage fluid.
Mingzhu Zhao +9 more
wiley +1 more source
Radiotherapy‐treated tumor membranes are integrated with Mn‐MOF nanoadjuvants to generate Mn@RM, a lymph node‐draining nanovaccine that delivers radiotherapy‐remodeled antigenic components. Mn@RM enhances dendritic cell activation, amplifies T cell‐mediated antitumor immunity, and synergizes with radiotherapy and PD‐1 blockade for combination cancer ...
Yiyu Wang +8 more
wiley +1 more source
From Policy to Practice: The Achievements, Challenges, and Outlook of Birth Registration in Ghana. [PDF]
Kyei-Gyamfi S +4 more
europepmc +1 more source
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu +14 more
wiley +1 more source
Spatially varying relationships between birth registration and influencing factors in Kenya, using a suite of geographically weighted regressions. [PDF]
Robert BN +7 more
europepmc +1 more source
CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu +13 more
wiley +1 more source
Missed at birth: a cross-sectional analysis of national determinants and subnational changes in birth registration coverage in Kenya, using 2014 and 2022 Demographic and Health Survey (DHS) data. [PDF]
Robert BN +6 more
europepmc +1 more source

