Results 121 to 130 of about 3,503 (263)

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág   +5 more
wiley   +1 more source

17O Quadrupole Coupling Constants in Water

open access: yesMagnetic Resonance in Chemistry, EarlyView.
In water clusters, first‐nearest‐neighbor interactions (1A and 1D) provide the largest contribution and are well captured by an additive donor–acceptor scheme, with improved accuracy upon inclusion of hydrogen bond distance dependence. Second nearest neighbor (D and A*) effects introduce smaller but systematic negative corrections, restoring near ...
Nabeeha Haque   +2 more
wiley   +1 more source

Information Design for Early‐Stage Dose‐Finding Trials

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT To enhance enrollment rates in early‐stage dose‐finding clinical trials, we propose an information design approach, where the clinical investigator (CI) commits to an information releasing mechanism (IRM) based on the treatment's uncertain efficacy and toxicity to encourage patients to participate in the trial.
Amin Khademi, Ningyuan Chen
wiley   +1 more source

Monitoring shallow geothermal aquifers with active‐source distributed acoustic sensing: A prognostic feasibility study on the University of Leeds Geothermal Campus

open access: yesNear Surface Geophysics, EarlyView.
Abstract The United Kingdom's shallow aquifers offer significant but underdeveloped geothermal energy resource. Seismic methods can help address this by improving the understanding of aquifer heterogeneity and potentially allowing long‐term monitoring of thermal plumes.
Adam D. Booth   +10 more
wiley   +1 more source

Scan for Success? Number Needed to Scan and Management Changes in Preoperative Otosclerosis: Quantitative Analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To quantify the cumulative number of images needed to scan (NNS) with preoperative high‐resolution temporal bone computed tomography (HR‐TBCT) to yield a change in management in patients undergoing primary stapes surgery for otosclerosis‐related hearing loss. Study Design Retrospective cohort.
Omer J. Ungar   +8 more
wiley   +1 more source

Regenerative Injection Laryngoplasty With Scaffold‐Forming Oligomer and Autologous Motor Endplate‐Expressing Cells: A 6‐Month Porcine Study

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Injection laryngoplasty is a standard‐of‐care intervention for unilateral vocal fold paralysis (UVFP), offering minimally invasive medialization with limited durability. We evaluated a regenerative injectable approach integrating an immunotolerant scaffold‐forming collagen (Oligomer) with autologous motor‐endplate expressing (MEE ...
Gabriel G. Sobczak   +9 more
wiley   +1 more source

Iron(III) ion reinforced P(NiPAAm‐co‐AA) beads as tunable smart organogels

open access: yesPolymer International, EarlyView.
Macroporous beads of PNiPAAm‐co‐AA copolymers were further crosslinked by iron(III) ions. The resulting beads are mechanically robust and reversibly responsive to a change of solvent from ethanol to ethyl acetate with half‐lives in the range of minutes.
Johannes Gmeiner   +2 more
wiley   +1 more source

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