Results 1 to 10 of about 30,877 (270)

Monitoring Serum Bisoprolol Concentrations in Patients With Heart Failure With Reduced Ejection Fraction: Results of a Pilot Study From Routine Health Care [PDF]

Pharmacology Research & Perspectives
Bisoprolol is a second‐generation, highly selective beta‐1 adrenergic receptor antagonist with various beneficial effects in patients with heart failure.
Ivana Kacirova, Marie Lazarova, Romana Urinovska, Jozef Dodulik, Diana Drienikova, Jan Vaclavik   +5 more
doaj   +5 more sources

Bisoprolol for patients with chronic obstructive pulmonary disease at high risk of exacerbation: the BICS RCT

Health Technology Assessment
Background Observational studies of people with chronic obstructive pulmonary disease using beta-blockers for cardiovascular disease indicate that beta-blocker use is associated with reduced risk of chronic obstructive pulmonary disease exacerbation ...
Graham Devereux, Seonaidh Cotton, Mintu Nath, Nicola McMeekin, Karen Campbell, Rekha Chaudhuri, Gourab Choudhury, Anthony De Soyza, Shona Fielding, Simon Gompertz, John Haughney, Amanda Lee, Graeme MacLennan, Alyn Morice, John Norrie, David Price, Philip Short, Jorgen Vestbo, Paul Walker, Jadwiga Wedzicha, Andrew Wilson, Olivia Wu, Brian Lipworth   +22 more
doaj   +4 more sources

Potential application of bisoprolol derivative compounds as antihypertensive drugs: synthesis and in silico study

Royal Society Open Science, 2023
Two bisoprolol derivatives, N-acetyl bisoprolol and N-formyl bisoprolol, belonging to the beta-blocker class of antihypertensive drugs, were synthesized using acetylation and formylation reactions. The yields of the reactions were determined to be 32.40%
Ni Putu Sani Oktaviani, Atthar Luqman Ivansyah, Muhammad Yogi Saputra, Nurrahmi Handayani, Nurdiani Fadylla, Deana Wahyuningrum   +5 more
doaj   +2 more sources

The Influence of EGCG on the Pharmacokinetics and Pharmacodynamics of Bisoprolol and a New Method for Simultaneous Determination of EGCG and Bisoprolol in Rat Plasma

Frontiers in Nutrition, 2022
Background and AimResearch has shown that green tea catechins may influence the activity of drug metabolizing enzymes and drug transporters. We examined whether epigallocatechin-3-gallate (EGCG) affected the pharmacokinetics and pharmacodynamics of ...
Weiwei Zeng, Weiwei Zeng, Sixian Lao, Sixian Lao, Yi Guo, Yi Guo, Yufeng Wu, Yufeng Wu, Min Huang, Min Huang, Brian Tomlinson, Guoping Zhong, Guoping Zhong   +12 more
doaj   +2 more sources

Forced degradation studies and structural characterization of related substances of bisoprolol fumarate in finished drug product using LC-UV-MS/MS [PDF]

Journal of the Serbian Chemical Society, 2022
Methods for determination of bisoprolol and related substances mostly use UV detection and a phosphate buffer and are not suitable for MS detection.
Lazarevska-Todevska Elena, Piponski Marjan, Stefova Marina   +2 more
doaj   +2 more sources

Influence of CYP2D6 and CYP3A5 Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients

Frontiers in Medicine, 2021
Purpose: This study was performed to investigate the effects of common polymorphisms in CYP2D6 and CYP3A5 on the plasma concentrations and antihypertensive effects of bisoprolol in hypertensive Chinese patients.Methods: One hundred patients with ...
Sze Wa Chan, Tanya T. W. Chu, Chung Shun Ho, Alice P. S. Kong, Brian Tomlinson, Brian Tomlinson, Weiwei Zeng   +6 more
doaj   +2 more sources

Development and validation of a fast and simple HPLC method for the simultaneous determination of bisoprolol and enalapril in dosage form [PDF]

Pharmacia, 2021
Aim. We aimed to develop and validate fast, simple, accurate, robust and rugged chromatographic method for simultaneous determination of bisoprolol fumarate and enalaril maleate in solid pharmaceutical dosage form, with using chaotropic strong chaotropic
Marjan Piponski, Trajan Balkanov, Liliya Logoyda   +2 more
doaj   +4 more sources

Pharmacotherapy efficacy and safety criteria based on spectral shifts in elder patients with arterial hypertension and coronary artery disease

Journal of Education, Health and Sport, 2017
The article is dedicated to development of homeostatic criteria of efficacy and safety of drugs combinations “lisinopril, bisoprolol, indapamide, isosorbide dinitrate, acetylsalicylic acid”.
V. A. Shtanko, N. V. Tofan, O. V. Khyzhnyak, V. B. Yablonska, S. A. Novikov   +4 more
doaj   +3 more sources

BISOPROLOL AND METFORMIN IN PATIENTS WITH ARTERIAL HYPERTENSION AND METABOLIC SYNDROME

Рациональная фармакотерапия в кардиологии, 2015
Aim. To compare efficacy of bisoprolol and bisoprolol+metformin combination in patients with arterial hypertension (AH) and metabolic syndrome (MS).Material and methods. 20 patients with AH and MS were involved in the study.
V. A. Nevzorova, N. V. Zakcharchuk, O. V. Nastradin, O. G. Pomogalova   +3 more
doaj   +3 more sources

Bisoprolol transdermal patch treatment for patients with atrial fibrillation after noncardiac surgery: A single-center retrospective study of 61 patients

SAGE Open Medicine, 2020
Objectives: Atrial fibrillation after surgery is associated with increased rates of heart failure and ischemic stroke, and extension of hospitalization. Bisoprolol is a β-blocker used to reduce heart rate and manage arrhythmias during atrial fibrillation.
Taku Yasui, Toru Oka, Wataru Shioyama, Makiko Oboshi, Masashi Fujita   +4 more
doaj   +1 more source