[Bisphosphonate-associated osteonecrosis of the jaw].
Schmerz (Berlin, Germany), 2016Bisphosphonates (BP) are used in the treatment of severe osteoporosis and metastasis of malignant diseases. A possible relationship between the occurrence of osteonecrosis of the jaw and BP therapy was first described in 2003. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is difficult to treat.
S, Koy +5 more
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Teriparatide’s role in the management of bisphosphonate-associated osteonecrosis of the jaw
Osteoporosis International, 20121. Recently, we published a model for the pathogenesis of bisphosphonate-associated osteonecrosis of the jaws (BON) based on perpetuation of attenuated bone remodeling as a result of the patient’s underlying disease, such as osteoporosis or malignant bone disease and its management with bisphosphonates; together, these factors undermine bone remodeling
G, Subramanian, S Y P, Quek
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Bisphosphonate‐associated osteonecrosis of the jaws: The limits of a conservative approach
Head & Neck, 2009AbstractBackground.An increasing number of cases of osteonecrosis of the jaws (ONJ) in patients treated with bisphosphonates has been reported in the literature. ONJ significantly affects the patients' quality of life and its management is still extremely difficult.Methods.A woman with ONJ secondary to therapy with zoledronic acid came to our attention
TIRELLI, GIAN CARLO +5 more
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Identification and Treatment of Bisphosphonate-Associated Actinomycotic Osteonecrosis of the Jaws
Implant Dentistry, 2011Osteonecrosis of the jaws (ONJ) is a condition characterized by necrotic exposed bone in the jaws of patients receiving intravenous or oral bisphosphonate therapy. A review of the medical and dental literature reveals that the pathoetiology of ONJ remains unknown and there is no established link that bisphosphonates are the primary cause of this bone ...
Cameron Y S, Lee +2 more
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Consequence of therapy discontinuation in bisphosphonate-associated osteonecrosis of the jaws
British Journal of Oral and Maxillofacial Surgery, 2009We report a patient with bisphosphonate-associated osteonecrosis of the jaws who developed pathological fractures of the upper and lower extremities after the suspension of treatment with bisphosphonates. Temporary discontinuation of the drugs does not alter the clinical course of the disease, and could result in the recurrence of bone pain and the ...
Lorena, Gallego, Luis, Junquera
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Clinical aspects and management of bisphosphonates-associated osteonecrosis of the jaws
Acta Odontologica Scandinavica, 2006An increasing incidence of osteonecrosis of the jaws (ONJ) in patients treated with intravenous bisphosphonates has been reported in the literature. The aim of this study was to evaluate the clinical aspects, diagnostic investigations, and management of ONJ associated with bisphosphonates in a series of 12 patients.Our patients included 1 asymptomatic ...
BIASOTTO, MATTEO +6 more
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Bisphosphonate‐associated osteonecrosis of the jaw: does it occur in children?
Clinical Endocrinology, 2008SummaryBackground Bisphosphonate use in adult patients has been linked to osteonecrosis of the jaw (ONJ). This complication has not been systematically assessed in a paediatric population receiving bisphosphonates.Objective To assess our cohort of paediatric patients treated with intravenous bisphosphonate for occurrence of ONJ.Design Observational ...
J J, Brown, L, Ramalingam, M R, Zacharin
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Bisphosphonate-associated osteonecrosis of the jaws
Journal of Oral and Maxillofacial Surgery, 2005MICHAEL R. MARKIEWICZ +3 more
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[Bisphosphonate-associated osteonecrosis of the jaws 1].
Nederlands tijdschrift voor tandheelkunde, 2007Bisphosphonates are generally administered either orally or intravenously. Orally administered bisphosphonates are primarilly used in the treatment of postmenopausal osteoporosis, glucocorticoid-induced osteoporosis, and Paget's disease. When orally administered, only about 1% is absorbed from the tractus from the tractus digestivus.
R H B, Allard +4 more
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Can children be affected by bisphosphonate-related osteonecrosis of the jaw? A systematic review
International Journal of Oral and Maxillofacial Surgery, 2020Juliana Bertoldi Franco +1 more
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