Results 61 to 70 of about 6,563 (227)

Comparative survival analysis of endodontic re‐treatment and single‐tooth implants: A retrospective cohort study using shared frailty modeling

Journal of Prosthodontics, EarlyView.
Abstract Purpose To compare the long‐term survival of nonsurgical endodontic re‐treatment versus single‐tooth implants and to identify independent demographic, systemic, and lifestyle predictors of failure using a statistical model that accounts for patient‐level clustering.
Georgios S. Chatzopoulos, Larry F. Wolff
wiley   +1 more source

Low awareness of medication-related osteonecrosis of the jaw among dentists: a systematic review with a medical and bioethical perspective

BMC Medical Ethics
Introduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious adverse drug reaction that can seriously affect the quality of life of patients if not promptly diagnosed and treated. To date, preventive measures have been the most effective
Martina Coppini, Sonia Arduini, Rodolfo Mauceri, Isabel Ascension Trujillo Perez, Giuseppina Campisi   +4 more
doaj   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

DENOSUMAB-RELATED OSTEONECROSIS OF THE JAWS: A CASE REPORT [PDF]

Journal of IMAB, 2017
Bisphosphonates are potent and effective drugs frequently used to prevent the skeletal complications associated with postmenopausal osteoporosis in women, to manage patients with multiple myeloma, hypercalcemia, and metastasis of cancer to the bone. The
Milena Petkova, Pavel Stanimirov
doaj   +1 more source

Bisphosphonate-related osteonecrosis of the jaw: an overview

, 2010
Bisphosphonates are widely used in the management of metastatic disease to bone and in diseases of altered bone turnover. Recently, multiple-case series and retrospective studies have established a relationship between necrotic bone lesions localized to ...
Ruggiero, S. L., Salvatore L. Ruggiero
core   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Radiographic Analysis of MRONJ in Osteoporotic and Oncologic Patients on Bisphosphonates or Denosumab

Oral Diseases, EarlyView.
ABSTRACT Introduction Medication‐Related Osteonecrosis of the Jaw (MRONJ) is a severe adverse effect of antiresorptive and antiangiogenic treatment, primarily in osteoporotic and oncologic patients. The disease is characterized by persistent jawbone necrosis that results in significant impairment of the quality of life of involved patients.
Omar Ghanaiem, Gavriel Chaushu, Daya Masri   +2 more
wiley   +1 more source

Is Fluorescence‐Guided Surgery Reliable for the Treatment of MRONJ? A Systematic Review and Meta‐Analysis

Oral Diseases, EarlyView.
ABSTRACT Background Identification of healthy bone margins is a critical step in the surgical resective treatment of medication‐related osteonecrosis of the jaw (MRONJ). Fluorescence‐guided surgery (FGS) has been proposed as a method to identify resection margins and improve clinical outcomes.
Paolo De Angelis, Alessandro Donato Tescione, Ivan Michele Aniceto, Cosimo Rupe, Gioele Gioco, Romeo Patini, Carlo Lajolo   +6 more
wiley   +1 more source

Time since last intravenous bisphosphonate and risk of osteonecrosis of the jaw in osteoporotic patients

Nature Communications
Medication-related osteonecrosis of the jaw is a rare but serious condition in which the jawbone fails to heal and becomes necrotic, typically after dental surgery in patients treated with bisphosphonates.
Jung-Hyun Park, Sung Hye Kong, Jungsil Lee, Jongmin Oh, Jae-Ryun Lee, Hyo-Jung Lee, Jin-Woo Kim   +6 more
doaj   +1 more source

Bisphosphonate-related osteonecrosis of the jaw complicated by Ludwig's angina

, 2015
Ludwig's angina is a life-threatening cellulitis that involves the submandibular and sublingual spaces. It often occurs after an infection of the roots of the teeth.
Shen, Shu-Huei, Chu, Yum-Kung, Yang, Rong-Hsin, Li, Wing-Yin   +3 more
core   +1 more source