Results 61 to 70 of about 178,855,135 (215)

Imaging findings in bisphosphonate-induced osteonecrosis of the jaws [PDF]

, 2010
Background. Bisphosphonates are drugs used in the treatment of lytic bone metastases, multiple myeloma, hyper-calcemia of malignant origin, osteoporosis, and diseases such as Paget’s disease. Recently osteonecrosis of the jaw has been associated with the
Katarina Popovic, Kočar, Miha, Katarina Surlan Popovic, Miha Kocar, Šurlan Popović, Katarina   +4 more
core   +1 more source

Bisphosphonate-related Osteonecrosis Of The Jaw: A Review Of The Literature [PDF]

, 2015
Bisphosphonates (BPs) are a class of drugs used to treat osteoporosis and malignant bone metastasis. BPs show high binding capacity to the bone matrix, especially in sites of active bone metabolism.
Sigua-Rodriguez E.A., De Brito A.C.R., Alvarez-Pinzon N., De Albergaria-Barbosa J.R., Da Costa Ribeiro R.   +4 more
core   +2 more sources

Low awareness of medication-related osteonecrosis of the jaw among dentists: a systematic review with a medical and bioethical perspective

BMC Medical Ethics
Introduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious adverse drug reaction that can seriously affect the quality of life of patients if not promptly diagnosed and treated. To date, preventive measures have been the most effective
Martina Coppini, Sonia Arduini, Rodolfo Mauceri, Isabel Ascension Trujillo Perez, Giuseppina Campisi   +4 more
doaj   +1 more source

Radiomics Analysis for Predicting Medication‐Related Osteonecrosis of the Jaw Using Computed Tomography

Oral Diseases, EarlyView.
ABSTRACT Objectives To determine whether pretreatment radiomics can predict medication‐related osteonecrosis of the jaw (MRONJ). Methods Patients with mandibular MRONJ at Hiroshima University Hospital (2009–2024) who underwent MDCT before initiating bone resorption inhibitors were retrospectively identified. Records from 2009 to 2020 were also reviewed
Masaru Konishi
wiley   +1 more source

Bisphosphonate-Related Osteonecrosis of the Jaw

, 2017
Introduction: Bisphosphonates are efficiently used to treat osteoporosis, bone metastases of malignant tumors, Paget`s disease and multiple myeloma. Bisphosphonate-related osteonecrosis of the jaw (BRONJ) represents a severe side effect, consisting of ...
Kolarov, Rossen, Dobrev, Desislav, Toncheva, Borislava, Rachev, Daniel   +3 more
core   +1 more source

Sequential Anabolic and Antiresorptive Treatment Promotes Medication‐Related Osteonecrosis of the Jaw in Mice

Oral Diseases, EarlyView.
ABSTRACT Objective To investigate the effects of sequential administration of romosozumab and denosumab on post‐extraction socket healing and osteonecrosis development in a murine tooth extraction model. Methods Forty female mice were randomly assigned to four groups: control (Ctrl), romosozumab (Rm), denosumab (Dmab), and sequential romosozumab ...
Seo‐Yeong An, Hae‐Seo Park, Reuben H. Kim, Moon‐Young Kim   +3 more
wiley   +1 more source

Bisphosphonate-related osteonecrosis of the jaw: an overview

, 2010
Bisphosphonates are widely used in the management of metastatic disease to bone and in diseases of altered bone turnover. Recently, multiple-case series and retrospective studies have established a relationship between necrotic bone lesions localized to ...
Ruggiero, S. L., Salvatore L. Ruggiero
core   +1 more source

BISPHOSPHONATE-INDUCED OSTEONETROCROSIS OF THE JAW IN CANCER PATIENTS: A HISTOPATHOLOGICAL STUDY

Медична наука України
Background. Osteonecrosis of the jaw associated with the use of bisphosphonates, such as zoledronic acid, occurs in patients with malignant tumors with metastatic bone lesions and is a severe complication that significantly reduces the quality of life ...
L.I. Volos, H.L. Stoliar
doaj   +1 more source

Acute Nontraumatic Clavicle Fracture Associated with Long-Term Bisphosphonate Therapy

Case Reports in Orthopedics, 2014
Cases of osteonecrosis of the jaw, insufficiency fractures and atypical low energy or atraumatic fractures of pelvis, femur (subtrochanteric/mid-shaft/distal-third), tibia, fibula, metatarsal, humerus, and ulna related to long-term bisphosphonate therapy
Shen Hwa Vun, Yahya Husami, Sajan Shareef, Diane Bramley   +3 more
doaj   +1 more source

Algorithm for Surgical Management in Patients in Treatment With Medication Associated With Osteonecrosis of the Jaws

Oral Surgery, EarlyView.
ABSTRACT Background Osteonecrosis of the jaws is associated with various drugs, including antiresorptives such as bisphosphonates and denosumab, as well as antiangiogenics. These drugs are used for the treatment of multiple diseases, notably osteoporosis, bone metastases, Paget's disease, osteogenesis imperfecta, malignant hypocalcaemia, among others ...
Rodríguez Naranjo Julia Alexandra, Gómez Hernández Kevin Andrew, Cabrera del Cid María Fernanda, Jerez Robalino James Philippe   +3 more
wiley   +1 more source