Results 91 to 100 of about 732,700 (303)

Heaps with bits

Theoretical Computer Science, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Svante Carlsson, Jingsen Chen, Christer Mattsson   +2 more
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The Role of the Equestrian Professional in Bridle and Bit Fit in the United Kingdom

Animals
To ensure the comfort of ridden horses, equipment including bridles and bits should be suitable and fit correctly. Horse owners employ a variety of equestrian professionals with varying degrees of responsibility regarding bridle and bit fit.
Kathryn Nankervis, Jane M. Williams, Diana Fisher, Russell MacKechnie-Guire   +3 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Entrevista a Luís Epele, director del Centro Científico Tecnológico -CCT- CONICET La Plata

, 2016
Bit&Byte conversó con el doctor en Física, Luís Epele. Director del Centro Científico Tecnológico -CCT- CONICET La Plata. La conversación tuvo como ejes centrales la investigación y la innovación vinculadas a la formación de profesionales. Además Epele
Bit & Byte
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

"Cuando se piensa en un solo tipo de usuario se deja afuera a muchos otros" : Entrevista a María del Carmen Malbrán

, 2016
La reconocida profesora y experta en temas vinculados a la educación, María del Carmen Malbrán, conversó con Bit&Byte. El diálogo se enmarcó sobre cómo las relaciones humanas son atravesadas por las nuevas tecnologías, generando acercamientos y ...
Bit & Byte
core  

Repensar la educación en función del cambio tecnológico [PDF]

, 2019
Bit&Byte conversó con el Dr. Alberto Dibbern, miembro de la Comisión Nacional de Evaluación y Acreditación Universitaria (CONEAU) acerca del impacto de las nuevas tecnologías en los procesos formales de enseñanza.
Bit & Byte
core  

Research and Development of PDC Bits for Geothermal Well Drilling

Journal of MMIJ
Polycrystalline diamond compact (PDC) bits, which are widely used in oil and gas well drilling, have begun to be used in geothermal well drilling. Mitsubishi Materials Corporation, K. Maikai Co., Ltd, and National Institute of Advanced Industrial Science
Kuniyuki MIYAZAKI, Takashi TAKEHARA, Masahiro YANO, Tetsuomi MIYAMOTO, Masatoshi TSUZUKI   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source