Results 41 to 50 of about 732,700 (303)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Las nuevas tecnologías y el cerebro del futuro [PDF]
Bit&Byte dialogó con el Dr. Facundo Manes y con el Dr.
Bit & Byte
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Two research contributions in 64-bit computing: Testing and Applications
Following the release of Windows 64-bit and Redhat Linux 64-bit operating systems (OS) in late April 2005, this is the one of the first 64-bit OS research project completed in a British university.
Chang, Victor
core +1 more source
Experiments and Investigations for the Personal High Performance Computing (PHPC) built on top of the 64-bit processing and clustering systems [PDF]
The motivation and objective for this paper is to demonstrate “Personal High Performance Computing (PHPC)”, which requires only a smaller number of computers, resources and space in the secure wireless home networking (WHN) environment. The PHPC is based
V. Chang, Chang, V., Chang, Victor
core +2 more sources
Numerical Analysis for Mechanical Properties of Bundled Integrate Structure Joints
[Objective] The U-BIT (underground bundled integrate tunnel) method can solve the problems of steel pipe sections inability in collaborative work and poor support efficiency of the traditional pipe curtain method.
JI Maojie +7 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
In view of the problem that the evolutionary mechanism of bit temperature during the drilling process is still unclear and the influencing factors are complex, this paper analyzes the causes of heat generation and the factors of heat production when the ...
Pengqi Qiu +4 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Desarrollos tecnológicos [PDF]
Bit&Byte destina este espacio para compartir con sus lectores algunas de las innovaciones tecnológicas que se han desarrollado en diferentes países del mundo durante los primeros meses del año.Facultad de ...
Bit&Byte, Bit & Byte
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