Results 201 to 210 of about 4,017,655 (334)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Rabies post-exposure prophylaxis in India: a SWOT analysis. [PDF]

Ther Adv Vaccines Immunother
Pardeshi G, Sharma P, Ittiel A.
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Shape Matters: Lemurs Eat Much Bigger Rounded Than Cubic Foods. [PDF]

Am J Biol Anthropol
Deutsch AR, Hartstone-Rose A.
europepmc   +1 more source

A Shape‐Adaptive, Performance‐Programmable, Self‐Healable and On‐Demand Destructible Robotic Skin via Self‐Strengthening Dynamic Silicone

Advanced Science, EarlyView.
Enabled by the distinctive inter‐ and intra‐chain siloxane exchange in commercially available silicones as the dielectric layer, the omni‐adaptive robotic skin (OmniAdapt) integrates multiple advanced functionalities: programmable sensing performance via the self‐stiffening dielectric material, application as BPM sensor, shape adaptivity for electronic
Wusha Miao, Lara S. Laamari, Jing Yu, Sanjay Schreiber, Lukas Heer, Jiacheng Cui, Jiayuan Huang, Hedan Bai   +7 more
wiley   +1 more source

Predictive bite force modelling of head and neck oncology patients for clinical mandibular reconstruction applications. [PDF]

Clin Oral Investig
Heins JI, Gareb B, Ten Brink R, Vosselman N, Halmos GB, Krushynska AO, Merema BBJ, Kraeima J, Witjes MJH.   +8 more
europepmc   +1 more source

Handling Time and Bite Mass Mechanisms in Large Herbivores: Contrasts between Sward Structure and Grazing Methods

, 2020
Jean Carlos Mezzalira, Lidiane Fonseca, Carlos César Mezzalira, Lenilson da Fonseca Rosa, Luan Carlos Pagani, Marco A. Ebbing, T. C. M. Genro, Paulo César de Faccio Carvalho, Carolina Bremm, Ricardo Souza Arruda Filho, Luis Henrique Silva Correia, Carlos A. Cangiano   +11 more
openalex   +1 more source

Organic Bulk‐Heterojunction‐Integrated Flexible Perovskite Photodetection Arrays for High‐Speed Broadband Optical Communication

Advanced Science, EarlyView.
A flexible broadband photodetector is realized by integrating a perovskite with an organic bulk‐heterojunction. It achieves high external quantum efficiency (EQE) (>80% visible, >60% near‐infrared (NIR)), ultralow dark current, and fast response, enabling self‐powered, high‐detectivity operation.
Xin Hong, Kanghui Ke, Yu Gao, Jiazhi Meng, Bohua Deng, Haoyu Huang, Zhichun Si, H. Y. Fu, Feiyu Kang, Guodan Wei   +9 more
wiley   +1 more source

Burden of dog bites and associated healthcare seeking behavior for rabies post-exposure prophylaxis in North and South Shahdara municipal zones of Delhi, India. [PDF]

BMC Public Health
Yathagiri N, Khan AM, Sharma R, Agarwal A, Nengminza Sangma RV.   +4 more
europepmc   +1 more source

Robotic Materials With Bioinspired Microstructures for High Sensitivity and Fast Actuation

Advanced Science, EarlyView.
In the review paper, design rationale and approaches for bioinspired sensors and actuators in robotics applications are presented. These bioinspired microstructure strategies implemented in both can improve the performance in several ways. Also, recent ideas and innovations that embed robotic materials with logic and computation with it are part of the
Sakshi Sakshi, Rohit Pratyush Behera, Hongyu Zhou, Yifan Wang, Hortense Le Ferrand   +4 more
wiley   +1 more source