Results 41 to 50 of about 5,531,537 (304)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Comportamento ingestivo diurno de vacas primíparas em pastagem nativa dominada por capim-annoni-2 com suplementação proteica e mineral em diversas estações climáticas Diurnal ingestive behaviour of pregnant heifers grazing on natural grasslands invaded by Eragrostis plana Ness as affected by protein and mineral supplements in the different climatic seasons

Revista Brasileira de Zootecnia, 2010
Avaliou-se a influência da suplementação proteica e mineral sobre o comportamento ingestivo de vacas primíparas em pastagem nativa dominada por capim-annoni-2 (Eragrostis plana Ness) recebendo suplementação com sal comum; sal mineral; sal proteinado; ou ...
Silvane Barcelos Carlotto, Renato Borges de Medeiros, Caius Barcellos de Pellegrini, Renata Porto Alegre Garcia, Celso Augusto Vargas Lisboa, João Carlos de Saibro   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Comportamento ingestivo e consumo de forragem por cordeiras em pastagem de milheto recebendo ou não suplemento Feeding behavior and forage intake of ewe lambs on pearl millet pasture with or without supplementation

Revista Brasileira de Zootecnia, 2010
Avaliaram-se o comportamento ingestivo e o consumo de matéria seca de cordeiras recebendo diferentes tipos de suplemento em pastagem de milheto (Pennisetum americanum (L.) Leeke).
Felipe Jochims, Cleber Cassol Pires, Letieri Griebler, Anderson Michel Soares Bolzan, Felipe Dotto Dias, Diego Barcelos Galvani   +5 more
doaj   +1 more source

The Effect of Bite Turbos on Mandibular Anterior Bracket Failure Rate: A Retrospective Study

, 2023
Introduction: Many factors influence the bond failure rate of brackets including malocclusion. It has been shown that bracket failure rates increase with increased overbite.
Meky, Mohamed
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Grazing ecology of female lambs on Italian ryegrass plus red clover pasture under different defoliation intensities Ecologia do pastejo por cordeiras em pastagem de azevém e trevo-vermelho sob diversas intensidades de desfolha

Revista Brasileira de Zootecnia, 2010
The relationship between pasture dynamics and ingestive behavior of female lambs was studied on Italian ryegrass (Lolium multiflorum Lam.) plus red clover (Trifolium pratense L.) mixture under a range of defoliation intensities.
Carine Lisete Glienke, Marta Gomes da Rocha, Daniele Gindri Camargo, Luciana Pötter, Anna Carolina Cerato Confortin, Vagner Guasso da Costa   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Performance and grazing behavior of growing goats supplemented with palm tree fruit

Revista Brasileira de Zootecnia, 2019
This study aimed to evaluate the performance and ingestive behavior of growing goats grazing on Tanzania guinea grass and fed diets containing 40% carnauba or tucum fruits.
Bruno Spindola Garcez, Arnaud Azevêdo Alves, Daniel Louçana da Costa Araújo, Maria Elizabete de Oliveira, Roberto Cláudio Fernandes Franco Pompeu, Marcos Cláudio Pinheiro Rogério, Antônia Leidiana Moreira, Isak Samir de Sousa Lima   +7 more
doaj   +1 more source

A new micro‐forceps for endoscopic ultrasound‐guided through‐the‐needle biopsy in the diagnosis of pancreatic cystic lesions: Single center experience

JGH Open, 2021
Background and Aim Endoscopic ultrasound (EUS)‐guided through‐the‐needle biopsy (TTNB) has improved the diagnostic algorithm of pancreatic cystic neoplasms (PCNs).
Serena Stigliano, Francesco Covotta, Francesco M Di Matteo   +2 more
doaj   +1 more source