Results 231 to 240 of about 7,507,294 (298)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

Advanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang, Zitong Huang, Yu Tao, Yunmei Zhang, Yufang Sun, Dongsheng Jiang, Weiwei Lu, Fuhai Ji, Gang Chen, Min Xu, Yuan Zhang, Jin Tao   +11 more
wiley   +1 more source

One Health implementation for rabies elimination in India by 2030: Progress, governance, challenges, and policy alignment. [PDF]

One Health
Phukan P.
europepmc   +1 more source

Sickle Trait Hemoglobin Does Not Influence Anopheles Biting Rates. [PDF]

Am J Trop Med Hyg
Markwalter CF, Kimachas E, Kirwa E, Kipkoech J, Kahindi S, Abel L, Han ZY, Mangeni JN, Obala AA, O'Meara WP, Taylor SM.   +10 more
europepmc   +1 more source

Human sand fly challenge elicits saliva-specific innate and type 1-polarized immunity that promotes Leishmania killing. [PDF]

Commun Biol
Abdeladhim M, Teixeira C, Ressner R, Hummer K, Dey R, Gomes R, de Castro W, de Araujo FF, Turiansky GW, Iniguez E, Meneses C, Oliveira F, Aronson N, Lacsina JR, Valenzuela JG, Kamhawi S.   +15 more
europepmc   +1 more source

Pre-exposure prophylaxis as a complementary vaccination strategy to reduce rabies in Kerala, India: a cost-effectiveness modelling study. [PDF]

Lancet Reg Health Southeast Asia
Luka MM, Nujum ZT, Asaria M, Ferguson EA, Harikumar S, Haydon DT, John RR, Hampson K.   +7 more
europepmc   +1 more source

Diagnostic performance of clinical symptom combinations for Crimean-Congo hemorrhagic fever in emergency department patients with reported arthropod bites, stings, or exposure. [PDF]

Trop Med Health
Bilgin Y, Sari FM, Sakal C, Cimen EY, Tanrıverdi O, Yurttutan AE, Binay UD.   +6 more
europepmc   +1 more source

Why are the ticks winning, and what can we do about it? [PDF]

Ticks Tick Borne Dis
Eisen L.
europepmc   +1 more source

Crimean-Congo haemorrhagic fever virus transmission: exploring perceptions of human-animal-tick interactions across six districts in Uganda

Kugler M, Mujumbusi L, Pickering L, Muhumuza R, Akugizibwe M, Obicho E, Apangu T, Umo E, Nuwamanya S, Ashraf S, Atim SA, Thomson EC, Lamberton PHL.   +12 more
europepmc   +1 more source

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A human bite

BMJ, 2012
A 26 year old man presented to the emergency department with a painful right ear after having been bitten three hours earlier during an altercation. He also reported receiving a blow to his right eye during the incident. He was normally fit and well and not taking any regular drugs. On examination, he was alert, orientated, and afebrile.
David A, Pettitt, Adeyinka, Molajo, Paul, McArthur   +2 more
openaire   +2 more sources