Results 161 to 170 of about 7,108 (196)
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Kappa Receptor Bivalent Ligands

Current Topics in Medicinal Chemistry, 2007
Bivalent ligands of kappa opioid agonists and antagonists, such as norBNI and BNI, are used as tools to elucidate the kappa receptor characteristics. Bivalent ligands may also be effective analgesics although none have this far been used clinically. Structure-activity relationships (SAR) and molecular modeling led to the development of a more potent ...
Xuemei, Peng, John L, Neumeyer
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Calcium: bivalent cation in the bivalent psychoses.

Biological psychiatry, 1979
Decreases in cerebrospinal fluid (CSF) calcium accompany mood elevation and motor activation in depressed patients undergoing treatment with ECT, lithium, and total sleep deprivation. Similarly, decreases in CSF calcium occur during acute psychotic agitation or mania.
J S, Carman, R J, Wyatt
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Bivalent cations in homozygous thalassemia

The Journal of Pediatrics, 1965
The duration of survival of pediatric patients with thalassemia major has been extendedby means of transfusion therapy. Late complications are now known to include skeletal fractures and myocardopathy with disturbances in cardiac conduction. Studies of calcium and magnesium have revealed decreased urinary excretion of these minerals from an early age ...
M E, ERLANDSON   +3 more
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Bivalent Metal Hydroxides

1977
In this article, the hydroxides Me(OH)2 of a number of bivalent metals, in part belonging to the first transition series, are discussed. These compounds are all more or less insoluble in water, of moderate chemical or thermal stability and have many properties in common, although there is considerable variability in the details.
H. R. Oswald, R. Asper
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Bivalent biogenic amine reuptake inhibitors

Bioorganic & Medicinal Chemistry Letters, 2003
A series of aryltropane-based bivalent ligands was prepared and investigated for binding potency and for their ability to inhibit reuptake of human dopamine, serotonin and norepinephrine transporters. The bivalent ligand 4, comprised of linking an aryltropane by an octamethylene spacer showed high efficacy for the human dopamine transporter and had a ...
Keith, Fandrick   +4 more
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Bivalent Histone Modifications and Development

Current Stem Cell Research & Therapy, 2018
Development is an epigenetic regulation dependent event. As one pretranscriptional regulator, bivalent histone modifications were observed to be involved in development recently. It is believed that histone methylation potentially takes charge of cell fate determination and differentiation.
Feifei, Li   +9 more
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Pragmatism and bivalence

International Studies in the Philosophy of Science, 1990
Abstract The success of the pragmatic account of truth is often thought to founder on the principle of bivalence—the principle which holds that every genuine statement in the indicative mood is either true or false. For pragmatists must, it seems, claim that the principle does not hold for theoretical statements and observation statements about the ...
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Am-bivalency towards DNA methylation

Nature Reviews Molecular Cell Biology, 2020
DPPA2 and DPPA4 maintain promoter bivalency and low levels of DNA methylation at certain lineage-specific genes.
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Bivalence and vagueness

Theoria, 1995
Etude du phenomene du vague a travers l'analyse de la these de la bivalence, selon laquelle l'adhesion au principe de bivalence est essentiel au realisme, d'une part, et a travers l'analyse du principe de bivalence, selon lequel chaque proposition est vraie ou fausse, d'autre part. Soulevant la question de l'elimination et de la precision d'un predicat
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Bivalent Covid-19 Vaccines

New England Journal of Medicine, 2023
Peter W, Marks, Robert M, Califf
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