Results 41 to 50 of about 7,108 (196)

Stoic Virtue: A Contemporary Interpretation [PDF]

open access: yes, 2020
The Stoic understanding of virtue is often taken to be a non-starter. Many of the Stoic claims about virtue – that a virtue requires moral perfection and that all who are not fully virtuous are vicious – are thought to be completely out of step with our ...
Siscoe, Wes
core  

Bivalence and Future Contingency [PDF]

open access: yes, 2018
This work presents an overview of four different approaches to the problem of future contingency and determinism in temporal logics. All of them are bivalent, viz. they share the assumption that propositions concerning future contingent facts have a determinate truth-value (true or false).
Carlo Proietti   +2 more
openaire   +5 more sources

Modal Logic and Modal Metaphysics: An Avicennian Division of Labour

open access: yesTheoria, EarlyView.
ABSTRACT This paper argues that Avicenna was both a necessitarian and a realist about contingency. The two aspects of his modal metaphysics are reconciled by arguing that Avicenna's modal metaphysics is founded on realism about essences: strictly speaking, an individual has no contingent properties, but a modal distinction can be made between the ...
Jari Kaukua
wiley   +1 more source

Negation, 'presupposition' and the semantics/pragmatics distinction [PDF]

open access: yes, 1998
A cognitive pragmatic approach is taken to some long-standing problem cases of negation, the so-called presupposition denial cases. It is argued that a full account of the processes and levels of representation involved in their interpretation typically ...
Carston, R
core   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani   +6 more
wiley   +1 more source

Dendrite Formation and Self‐Healing Mechanism in Ionic Liquid‐Based Magnesium Batteries

open access: yesAdvanced Energy Materials, Volume 16, Issue 11, 18 March 2026.
This graphical illustration highlights the importance of operating Mg batteries within a safe operating current density (SOCD) range. Beyond this range, Mg batteries are susceptible to dendrite formation. However, when cycling a dendritic cell with a highly thermally stable electrolyte, a self‐heating effect occurs.
Omar W. Elkhafif   +5 more
wiley   +1 more source

Granice poznania a spór między realizmem i antyrealizmem (COGNITIVE LIMITS AND THE REALISM/ANTI-REALISM DEBATE) [PDF]

open access: yesAnaliza i Egzystencja, 2006
According to metaphysical realism, there are truths that we can understand but cannot even in principle come to know, whereas according to anti-realism, there are no such truths.
Sven Rosenkranz
doaj  

Temporal Truth and Bivalence: an Anachronistic Formal Approach to Aristotle’s De Interpretatione 9

open access: yesRevista de Filosofia Antiga, 2023
Regarding the famous Sea Battle Argument, which Aristotle presents in De Interpretatione 9, there has never been a general agreement not only about its correctness but also, and mainly, about what the argument really is.
Luiz Henrique Lopes dos Santos
doaj  

TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis.

open access: yesPLoS Pathogens, 2020
TNF-α- as well as non-TNF-α-targeting biologics are prescribed to treat a variety of immune-mediated inflammatory disorders. The well-documented risk of tuberculosis progression associated with anti-TNF-α treatment highlighted the central role of TNF-α ...
Ainhoa Arbués   +5 more
doaj   +1 more source

Molecular Glue Degraders Redefining Targeted Therapies From Discovery to Therapeutic Applications

open access: yesMedComm – Oncology, Volume 5, Issue 1, March 2026.
Molecular glue degraders (MGDs) constitute an emerging class of therapeutic agents poised to revolutionize the paradigm of targeted drug discovery. By reprogramming E3 ubiquitin ligases to degrade proteins of interest (POI) via a transient formation of a ternary complex mediated by protein–protein interactions, MGDs surpass the intrinsic limitations of
Jinfeng Wen   +3 more
wiley   +1 more source

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