Results 151 to 160 of about 563,810 (336)

Characterization of CD123 expression by mast cells in systemic mastocytosis with multicolor flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Systemic mastocytosis (SM) is a clonal mast cell (MC) disorder characterized by aberrant immunophenotypes, including expression of CD25, CD2, and occasionally CD30. CD123, the α‐subunit of the interleukin‐3 receptor, is a therapeutic target in hematologic malignancies and has been reported to be expressed on neoplastic MCs by ...
Ryan C. Shean, Tracy I. George, David P. Ng   +2 more
wiley   +1 more source

Superior Intracellular Detection of Cytokines, Transcription Factors, and Phosphoproteins by CyTOF Compared With Fluorescent Cytometry

Cytometry Part A, EarlyView.
ABSTRACT Unraveling biological complexity, such as immune subset distribution in infectious disease(s), autoimmunity, or tumor heterogeneity, requires technologies capable of single‐cell proteomic analysis such as flow cytometry. Surface phenotyping alone is often insufficient, as interrogating functional capacity is required to determine cellular ...
Michael J. Cohen, Erika L. Smith‐Mahoney, Madison Bailey, Ling Wang, Lauren J. Tracey, Laura Polanco, David King, Christina Loh, Amedeo J. Cappione III, Anna C. Belkina, Jennifer E. Snyder‐Cappione   +10 more
wiley   +1 more source

Unveiling spatial heterogeneity in urban underground space development patterns and mechanisms for differentiated planning: A points of interest‐based study of Shanghai

Deep Underground Science and Engineering, EarlyView.
This study investigated the spatial patterns and development mechanisms of urban underground space (UUS) in Shanghai using underground points of interest data. It revealed distinct development mechanisms between the main city and suburbs, highlighting the need for differentiated UUS planning and policies to optimize underground space resources ...
Chenxiao Ma, Fangle Peng, Yongkang Qiao, Yunhao Dong   +3 more
wiley   +1 more source

‘MultiTraits': an integrated R package for analysis and visualization of multidimensional plant traits

Ecography, EarlyView.
The multidimensional characteristics of plant traits and their trade‐offs are central to ecology. However, there is a lack of systematic and standardized tools for analyzing these intricate relationships. To fill this gap, we developed the ‘MultiTraits' R package, which incorporates four complementary analytical modules: competitors–stress tolerators ...
Yan He, Zhaogang Liu, Jiangshan Lai, Lingfeng Mao   +3 more
wiley   +1 more source

Environmental heterogeneity and spatial variation mediates plant diversity and ecosystem stability in mountain ecosystems of the Mediterranean Andes

Ecography, EarlyView.
Globally, mountains are highly diverse ecosystems that serve as natural laboratories for testing ecological theories, while providing vital ecosystem services. Their biodiversity arises from the interaction between elevational gradients and topographic complexity, which generate strong variation in environmental conditions across short spatial scales ...
Laura C. Pérez‐Giraldo, José M. Cerda‐ Paredes, Dylan Craven, Javier Lopatin   +3 more
wiley   +1 more source

Cross‐scale interactions mediate local drivers of nonnative species richness

Ecography, EarlyView.
Many well‐supported hypotheses seek to explain drivers of nonnative species richness across spatial scales, but evidence for common patterns among regions and taxa remains inconclusive. This study investigates why consistent patterns are elusive by estimating and assessing cross‐scale interactions, wherein large‐scale factors contextualize patterns ...
Lily M. Thompson, William K. Annis, Stephen R. Midway, Julian D. Olden, Brandon K. Peoples   +4 more
wiley   +1 more source

Genome-annotated bivariate analysis of shared heritability in autoimmune hepatitis with psychiatric comorbidity. [PDF]

Sci Rep
Liu L, Chen J, Chen T, Li J, Wang Q.
europepmc   +1 more source

Migration speed, timing, and long‐term shifts in age structure in North American passerines during fall migration

Ecography, EarlyView.
Migration is challenging for birds, especially juveniles, who experience high mortality rates during migration. The challenge is exacerbated in the Anthropocene, contributing to widespread population declines. Conservation efforts focused on increasing juvenile survival could bolster population recovery.
Dylan M. Osterhaus, Martha J. Desmond, Timothy F. Wright   +2 more
wiley   +1 more source

Improved bivariate analysis of canola survivability against blackleg disease. [PDF]

Theor Appl Genet
Thavarajah T, Walter J, Taylor J.
europepmc   +1 more source

The difficult discussion on the deactivation of implantable cardioverter devices at the end of life: a systematic review

ESC Heart Failure, Volume 12, Issue 2, Page 733-760, April 2025.
Abstract Implantable cardioverter defibrillators (ICDs) reliably prevent death due to life‐threatening arrhythmias; this may become less relevant in people with more severe heart failure who are reaching the end of life (EOL). This review aimed to explore the ICD deactivation process and identify ethical issues, especially around the initiation of ...
Siobhan C. Murray, Claire McNamara, Anna V. Chatzi   +2 more
wiley   +1 more source