Results 51 to 60 of about 15,459 (272)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

Uncertainty quantification via polynomial chaos expansion of myocardial fibre orientation and cardiac activation patterns

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Graphical representation of methods. We implemented three biventricular geometric models (Zenger et al., 2020) with rule‐based myocardial fibre orientations (Bayer et al., 2018). We evaluated variability in the fibre orientation via four sets of parameter distributions to determine the role of the primary and imbrication angles ...
Lindsay C. R. Tanner   +8 more
wiley   +1 more source

Simple and non-invasive diagnostics of a broad complex tachycardia in a device patient. [PDF]

open access: yes, 2015
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked Files.
Colman, Jack M   +2 more
core   +1 more source

Improvement of Left Ventricular Function by Permanent Direct His-Bundle Pacing in a Case with Dilated Cardiomyopathy

open access: yesJournal of Arrhythmia, 2006
The patient was a 67-year-old female diagnosed with dilated cardiomyopathy. She had chronic atrial fibrillation (AF) with bradycardia and low left ventricular function (left ventricular ejection fraction (LVEF) 40%). She was admitted for congestive heart
Yukiko Sashida, MD   +5 more
doaj   +1 more source

Minimizing hardware using physiological conduction system pacing: A case

open access: yesIHJ Cardiovascular Case Reports, 2020
Ventricular activation via the specialized His Purkinje system results in synchronous bi-ventricular contraction with an endocardial to epicardial activation wavefront.
Vivek Kumar   +2 more
doaj   +1 more source

Electrophysiological characterization of pre‐adolescents born with intrauterine growth restriction: insights from clinical and computational data

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Depolarization and repolarization duration analysis was conducted in preadolescent groups with IUGR and controls using a 12‐lead ECG. Principal component analysis was applied over the 12‐lead ECGs to generate spatially transformed leads better suited for robust ECG fiducial points detection.
Freddy L. Bueno‐Palomeque   +5 more
wiley   +1 more source

Biventricular Pacing in Normal Hearts

open access: yesReviews in Cardiovascular Medicine, 2012
For more than half a century, pacemakers have proven to be one of the most successful medical interventions. In an effort to approximate normal cardiac physiology, pacemakers have evolved from simple to highly sophisticated devices. There is a growing demand, not only to improve overall mortality and safety in patients with ...
Tariq, Bhat   +5 more
openaire   +2 more sources

Effects of AV delay programming on ventricular resynchronisation: role of radionuclide ventriculography [PDF]

open access: yes, 2018
Purpose: Optimal atrioventricular delay (AVD) setting for cardiac resynchronisation therapy, i.e. biventricular pacing in patients with heart failure, remains a formidable challenge.
Brunckhorst, Corinna   +9 more
core  

Indexed maximal left atrial volume predicts response to cardiac resynchronization therapy [PDF]

open access: yes, 2013
Aims Cardiac resynchronization therapy (CRT) has shown morbidity and mortality benefits in patients with advanced congestive heart failure (HF). Since about one-third of the patients did not appear to respond to CRT, it would seem reasonable to try to ...
Casali, Edoardo   +7 more
core   +1 more source

Biventricular pacing and heterogeneity of ventricular repolarization in heart failure patients

open access: yesHeart International, 2006
Objective: The aim of our study was to evaluate the effect of cardiac resyncronization therapy (CRT) on QT dispersion (QTd), JT dispersion (JTd) and transmural dispersion of repolarization (TDR), markers of heterogeneity of ventricular repolarization in ...
Raffaele Calabrò   +8 more
doaj   +1 more source

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