Results 211 to 220 of about 20,884 (264)

Distinct Brain Drivers and Shared Cerebello–Cortical Input in ADCY5 and SGCE Hyperkinetic Movements

Movement Disorders, EarlyView.
Resting‐state fMRI and effective connectivity revealed distinct cerebellar–basal ganglia–cortical interactions in ADCY5 (MxMD‐ADCY5) and SGCE (MYC/DYT‐SGCE) related movement disorders. The cerebellum modulated cortex directly in MYC/DYT‐SGCE, but indirectly via basal ganglia‐cerebellar projections in MxMD‐ADCY5, which also showed reduced subthalamic ...
Clément Tarrano, Cécile Galléa, Asya Ekmen, Cécile Delorme, Eavan M. McGovern, Quentin Salardaine, Lina Daghsen, Manon Gomes, Vanessa Brochard, Eoin Mulroy, Kailash P. Bhatia, Carlo Fusco, Miryam Carecchio, Norbert Brüggemann, Alexander Münchau, Victoria Gonzalez, Diane Doummar, Christine Tranchant, Mathieu Anheim, Philippe Damier, Florence Riant, Mohamed Doulazmi, Agathe Roubertie, Caroline Dubacq, Oriane Trouillard, Romain Valabregue, Mélanie Didier, Benoit Beranger, Pierre Pouget, Marie Vidailhet, Sabine Meunier, Aurélie Méneret, Yulia Worbe, Emmanuel Roze   +33 more
wiley   +1 more source

Morphea En Coup De Sabre Treated With Combination Hyaluronic Acid Filler and Neuromodulator: A Case Report. [PDF]

Cureus
Jensen C, Remington BK.
europepmc   +1 more source

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

Recurrent hepatocellular carcinoma treated by laparoscopic non-anatomical liver resection via the retroperitoneal approach: a case report. [PDF]

Front Surg
Zhang K, Liu Y, Liu B, Ge R.
europepmc   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay, Lynn C. Lunsonga, Peter E. Light, Khaled Barakat   +3 more
wiley   +1 more source

Clinical Spectrum and Outcomes of Melioidosis: An Eight-Year Study. [PDF]

Cureus
Radhakrishnan C, Kunhumon SP, K TN, V U, S R, Bk A, Dhanasooraj D.   +6 more
europepmc   +1 more source

Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite, Tom Da‐Silva Faria, Marie Shannon Soulez, Khaoula Bouazizi, Perrine Marsac, Elie Mousseaux, Jérôme Lamy, Moussa Gueda Moussa, Olivier Piot, Jacques Feignoux, Daniel Giese, Nicolas Badenco, Estelle Gandjbakhch, Alban Redheuil, Mikaël Laredo, Emilie Bollache, Nadjia Kachenoura   +16 more
wiley   +1 more source

Inertial‐Based LQG Control: A New Look at Inverted‐Pendulum Stabilization

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Linear‐quadratic Gaussian (LQG) control is a well‐established method for optimal control through state estimation, particularly in stabilizing an inverted pendulum on a cart. In standard laboratory setups, sensor redundancy enables direct measurement of configuration variables using displacement sensors and rotary encoders. However, in outdoor
Daniel Engelsman, Itzik Klein
wiley   +1 more source

The exquisite link between potassium homeostasis regulation and cardiovascular health: exploration and analysis. [PDF]

Front Physiol
Wang C, Huang X, Zhang Z, Lin D, Huang S.   +4 more
europepmc   +1 more source

Harnessing virus-specific T cells: expanding therapeutic strategies across diverse populations. [PDF]

Blood Adv
Djassemi N, Hanisch B, Motta C, Maghzian N, Vatsayan A, Durkee-Shock JR, Keller MD.   +6 more
europepmc   +1 more source