Results 231 to 240 of about 535,763 (276)

On the Importance of Correct Snake Identification. Comment on Chippaux et al. Snakebites in Cameroon by Species Whose Effects Are Poorly Described. Trop. Med. Infect. Dis. 2024, 9, 300. [PDF]

Trop Med Infect Dis
Wüster W, Warrell DA, Williams DJ.
europepmc   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

EEG-based minimum spanning tree analysis reveals network disruptions in Alzheimer's disease spectrum: an observational study. [PDF]

Front Aging Neurosci
Ye X, Yan Y, Wang Y, Shi J.
europepmc   +1 more source

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Impact of removal of the lateral orbital rim on intraorbital pressure during endoscopic trans-orbital approach (ETOA): a cadaveric study. [PDF]

Acta Neurochir (Wien)
Strangio A, Sonfack JDN, Comeau MO, Gago G, Moreau A, Coté M, Champagne PO.   +6 more
europepmc   +1 more source

Initial treatment approaches for nodular gastric antral vascular ectasia: A comparison of endoscopic band ligation and thermal therapies. [PDF]

World J Gastrointest Endosc
Cooper JA, Statham E, Holyfield A, Shoreibah MG, Peter S.   +4 more
europepmc   +1 more source

An Investigation of the Modulating Effects of Sensory Stimulation and Transcranial Magnetic Stimulation on Memory-Related Brain Activity. [PDF]

Brain Sci
Nikolin S, Wang M, Moffa A, Huang H, Xu M, Pande SR, Martin D.   +6 more
europepmc   +1 more source

Sub-sarcomeric regulation of thin and thick filaments in skeletal muscle myofibrils

Sliogeryte K, Fusi L.
europepmc   +1 more source