Results 61 to 70 of about 132,902 (232)

Cyanobacteria Associated with Coral Black Band Disease in Caribbean and Indo-Pacific Reefs [PDF]

open access: yesApplied and Environmental Microbiology, 2003
ABSTRACT For 30 years it has been assumed that a single species of cyanobacteria, Phormidium corallyticum , is the volumetrically dominant component of all cases of black band disease (BBD) in coral.
Jorge, Frias-Lopez   +3 more
openaire   +2 more sources

Prevalence, Insidence and Progression Black-band Disease on Scleractinian Coral (Montipora spp) in Shallow Water of Pari Islands

open access: yesIlmu Kelautan, 2015
Black-band disease (BBD) is a persistent disease that cause the decline of the coral reef ecosystems, which is still slightly recorded in Indonesia, including in Pari Island, Thousand Islands.
Michael Delpopi   +3 more
doaj   +1 more source

Nail disorders in skin of color: Approach to onychoscopic diagnosis

open access: yesClinical Dermatology Review, 2020
Onychoscopy provides a better understanding of nail lesions in terms of diagnosis, monitoring of progression and response to treatment. Author have put forward a simplified way to approach to a nail lesion by onychoscopy.
Balachandra S Ankad   +2 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Black phosphorus-Au-thiosugar nanosheets mediated photothermal induced anti-tumor effect enhancement by promoting infiltration of NK cells in hepatocellular carcinoma

open access: yesJournal of Nanobiotechnology, 2022
Background Hepatocellular carcinoma (HCC) is a heterogeneous cancer required combination therapy, such as photothermal therapy and chemotherapy. In recent years, cancer immunotherapies are rapidly evolving and are some of the most promising avenues to ...
Changchang Jia   +9 more
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Can Shading Drive the Transition from Black Band Disease to a Cyanobacterial Patch-like Stage in Montipora Corals?

open access: yesDiversity
Black band disease (BBD), which overgrows and kills scleractinian coral, is known to have various phases. The initial phase is the cyanobacterial patches (CPs) phase, followed by the intermediate phase (IP), and finally the mature BBD phase.
Rocktim Ramen Das   +3 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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