Results 201 to 210 of about 46,241 (258)

Tumor‐Specific Delivery of CD28 siRNA via Lyso‐PC C‐16 Modified Lipid Nanoparticles Overcomes Anti‐PD‐1 Resistance by Remodeling Tumor Microenvironment

Advanced Science, EarlyView.
This study develops 16:0 LPC‐modified lipid nanoparticles (LPC‐LNPs) with cancer cell specificity by exploiting altered tumor lipid metabolism. LPC‐LNPs encapsulating Cd28 small interfering RNA (LPC‐LNP‐Cd28) knock down cancer cell CD28 without affecting T cells, inflame the tumor microenvironment, and overcome anti‐PD‐1 resistance.
Yangyang Chai, Keyu Wang, Jiali Fang, Shaorui Jia, Yansong Shi, Wanfeng Gao, Xinpeng Liu, Jiaqiang Li, Zenghui Cui, Yazhi Qian, Xiaosu Chen, Dan Ding, Xuetao Cao   +12 more
wiley   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

Computation‐Guided Control of Excited‐State Deactivation through Modulation of Conical‐Intersection Accessibility by Donor–Acceptor Asymmetry in Bridged Stilbene AIE Luminogens

Advanced Science, EarlyView.
Donor–acceptor asymmetry modulates conical‐intersection accessibility and topology in bridged stilbenes, providing mechanistic insight into excited‐state deactivation and aggregation‐induced emission (AIE). ABSTRACT A computation‐guided investigation of asymmetric donor–acceptor bridged stilbenes reveals structure–property relationships governing ...
Takuya Tanaka, Satoshi Suzuki, Hirosato Koyanagi, Kiyoshi Miyata, Riki Iwai, Kazunobu Igawa, Ken Onda, Ben Zhong Tang, Gen‐ichi Konishi   +8 more
wiley   +1 more source

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Black Bears and the Iroquoians:

2020
The study presented in this chapter uses archaeological and ethnohistorical data to discuss the role of black bears (Ursus americanus) among Pre-Contact Iroquoian societies from Northeastern North America. This role is proving to be complex and multifaceted, and the analysis of the archaeological and ethnohistorical records provide contradictory ...
Christian Gates St-Pierre, Claire St-Germain, Louis-Vincent Laperrière-Désorcy   +2 more
openaire   +1 more source

Black Bear

Ploughshares, 2013
The Winter 2013-14 issue of Ploughshares. Ploughshares is an award-winning journal of new writing. Two out of each year’s three issues are guest-edited by prominent writers who explore different personal visions, aesthetics, and literary circles, with the Winter issue staff-edited.
openaire   +1 more source

Cryptosporidiosis in a Black Bear in Virginia

Journal of Wildlife Diseases, 1999
Cryptosporidiosis has not been previously reported in black bears in North America, either free-roaming or captive. However, oocysts have been documented in two captive Malayan sun bears (Helarctos malayanus) located in zoological parks in Taiwan. Developmental stages of Cryptosporidium parvum were observed in tissue sections from the small intestine ...
R B, Duncan, D, Caudell, D S, Lindsay, H D, Moll   +3 more
openaire   +2 more sources

Spinal Decompression in a Black Bear

Journal of the American Veterinary Medical Association, 1980
SUMMARY A 17-year-old black bear was examined because of posterior paralysis. Radiography revealed a narrowed disk space at T10–11, indicating a ruptured intervertebral disk. Subsequently, a dorsolateral hemilaminectomy was performed. Recovery from paralysis was slow because of the size of the animal (127 kg) and lack of appropriate physical therapy ...
J B, Nichols, M L, Dulisch, J G, Sikarskie, M A, McNamara   +3 more
openaire   +2 more sources

HELMINTHS OF THE BLACK BEAR IN QUEBEC

Journal of Wildlife Diseases, 1977
Twenty-one complete carcasses of black bears, Ursus americanus , together with 34 intestinal tracts, 86 diaphragms and 168 faecal droppings collected between June, 1971 and November, 1972 in the Province of Quebec were examinel for helminths. Species found and their prevalence were as follows: Dirofilaria ursi in 57%; Uncinaria yukonensis in 6 ...
J L, Frechette, M E, Rau
openaire   +2 more sources

Black polar bears

Nature, 1974
WHITE coloration of many animals in cold environments decreases the possibility of visual detection because of the lack of contrast between the animal and its white background. White hair thus provides concealing coloration for prey species such as arctic hare (Lepus arcticus), and for predators such as the polar bear (Ursus maritimus) and arctic fox ...
D. M. LAVIGNE, N. A. ØRITSLAND
openaire   +1 more source

Black Bear

2022
Michael Schaub, Marc Kéry
openaire   +1 more source