Results 251 to 260 of about 238,447 (346)

Single‐Field Evolution Rule Governs the Dynamics of Representational Drift in Mouse Hippocampal Dorsal CA1 Region

open access: yesAdvanced Science, EarlyView.
Long‐term hippocampal place‐code dynamics are investigated using calcium imaging across weeks of maze navigation. Analyses reveal a novelty‐irrelevant Single‐Field Evolution Rule (SFER), where active fields promote persistence and inactive fields decline.
Cong Chen   +10 more
wiley   +1 more source

TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
TNEA improves cognition in 5xFAD mice by modulating parvalbumin‐positive interneurons in hippocampal CA1. TNEA enhances gamma oscillations during rest and theta power during novel object recognition, restoring excitation/inhibition balance. These findings support TNEA as a minimally invasive therapy for Alzheimer's disease.
Zhongzhao Guo   +15 more
wiley   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

open access: yesAdvanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang   +13 more
wiley   +1 more source

A novel energy efficient QoS secure routing algorithm for WSNs. [PDF]

open access: yesSci Rep
Fei H   +6 more
europepmc   +1 more source

Positive Feedback Organic‐on‐Silicon Upconversion Devices

open access: yesAdvanced Science, EarlyView.
Positive optoelectronic feedback is achieved by depositing a tandem OLED on top of a heterojunction Si photodiode. The resulting hybrid device is bistable and upconverts near‐infrared light (λ = 1050 nm) to visible light (λ = 570 nm) with a photon‐to‐photon upconversion yield of up to 900%.
Raju Lampande   +5 more
wiley   +1 more source

Wavelength Tunable Pulsed Lasers Enabled by a Versatile Metafiber Functioning as Both Saturable Absorber and Filter

open access: yesAdvanced Science, EarlyView.
Schematic diagram of wavelength‐tunable pulsed laser based on metafiber‐FP (Fabry‐Perot). The alcohol solution is filled inside the FP cavity to simultaneously form a spectral filter and a saturable absorber. By adjusting the refractive index value and temperature inside the cavity, the tunable filtering effect is introduced to realize wavelength ...
Bo Fu   +8 more
wiley   +1 more source

Rapid Arbitrary‐Shape Microscopy of Unsectioned Tissues for Precise Intraoperative Tumor Margin Assessment

open access: yesAdvanced Science, EarlyView.
This study presents a novel microscopic imaging system capable of rapid, section‐free scanning of irregular tissue surfaces, delivering high sensitivity for detecting cancer cell clusters during intraoperative tumor margin assessment. Abstract Rapid and accurate intraoperative examination of tumor margins is crucial for precise surgical treatment, yet ...
Zhicheng Shao   +17 more
wiley   +1 more source

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