Results 21 to 30 of about 1,923 (263)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Distorted Love: Mapplethorpe, the Neo/Classical Sculptural Black Nude, and Visual Cultures of Transatlantic Enslavement

open access: yesImaginations: Journal of Cross-Cultural Media Studies, 2019
In the fall of 2016 and the winter of 2017, the Montreal Museum of Fine Arts exhibited a retrospective of photography by Robert Mapplethorpe (1946-1989) entitled “Focus: Perfection.” Tenets of queer possibility exhibited in the “Sculptural Body” portion ...
Lindsay Nixon
doaj   +1 more source

The critique of modernity from the Caribbean: black readings in (white) philosophy of history

open access: yesPoligramas, 2020
This paper reflects, first, on the Eurocentric condition of the theories of secularization and their disregard of the incidence of the conquest, colonialism and slavery on the rise of Modernity.
Florencia Bonfiglio
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Black Theology of liberation: A theology of life in the context of Empire

open access: yesVerbum et Ecclesia, 2015
The cry for life by the peoples of the global South and all the victims of the vicious antics of Empire is our hope. Living against the logic of Empire is rebellion against the life killing order of Empire.
Vuyani S. Vellem
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Anti-Semitism, Anti-Marxism, and Technophobia: The Fourth Volume of Martin Heidegger’s Black Notebooks (1942–1948)

open access: yestripleC: Communication, Capitalism & Critique, 2015
The fourth volume of Martin Heidegger’s Schwarze Hefte (Black Notebooks) was published in March 2015. It contains philosophical notes written in the years 1942–1948.
Christian Fuchs
doaj   +1 more source

Genealogies of Black Modernities

open access: yesAmerican Literary History, 2020
Abstract This essay introduces the major themes and concerns of “Genealogies of Black Modernity in the Long Nineteenth Century,” a special issue of American Literary History. How does modernity look when read through Black diasporic literary production in the long nineteenth century, broadly conceived?
openaire   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

The Reception of Bantu Divination in Modern South Africa: African Traditional Worldview in Interaction with European Thought

open access: yesReligions
Bantu African divination is firmly established in South Africa in the context of modernity and is protected, endorsed and regulated by law. It is received in the therapeutic field.
Ullrich Relebogilwe Kleinhempel
doaj   +1 more source

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