Results 111 to 120 of about 3,052,756 (265)

Anifrolumab Treatment Leads to Rapid Reduction in Urinary Biomarkers of Intrarenal Inflammation in Lupus Nephritis: Results From the Phase 2 Randomized Trial

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is one of the most severe manifestations of systemic lupus erythematosus (SLE) and is partially driven by type I interferon signaling. Anifrolumab, an approved treatment for patients with SLE, has been investigated in a phase 2 trial in patients with LN receiving standard therapy (TULIP‐LN, ClinicalTrials.gov identifier ...
Andrea Fava, Michelle Petri, Patrick G. Gavin, Eszter Csomor, Philip Z. Brohawn, Daniel Muthas, Adam Platt, Catharina Lindholm, Nicola Ferrari   +8 more
wiley   +1 more source

Barriers and facilitators to the engagement of physical activity among Black and African American cancer survivors during and after treatments. [PDF]

Support Care Cancer, 2023
Hirschey R, Xu J, Lea DF, Milner JL, Duggins P, Coleman K, Teal R, Carda-Auten J, Giannone K, Hilton A, Waheed M, Triglianos T, Wheeler SB, Valle CG, Bryant AL.   +14 more
europepmc   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

Comparison of Cardiorespiratory Fitness in Black or African American Versus Caucasian Patients With Heart Failure. [PDF]

J Cardiopulm Rehabil Prev, 2022
Canada JM, Park TS, Ravindra K, Chiabrando JG, Del Buono MG, van Wezenbeek J, Trankle CR, Kadariya D, Keen L, Carbone S, Billingsley H, Wohlford GF, Arena R, Van Tassell BW, Abbate A.   +14 more
europepmc   +1 more source

Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao, Yash Pershad, J. Brett Heimlich, Michelle Ormseth, C. Michael Stein, Brian Sharber, Caitlyn Vlasschaert, Alexander G. Bick, Robert W. Corty   +8 more
wiley   +1 more source

A Descriptive, Post Hoc Analysis of Efficacy and Safety of Risankizumab in Diverse Racial and Ethnic Patient Populations With Moderate-to-Severe Psoriasis

Dermatology and Therapy
Introduction Historically, patients with skin of color are underdiagnosed with psoriasis and underrepresented in clinical trials. In this study, we assess the efficacy and safety of risankizumab in patients with moderate-to-severe plaque psoriasis by ...
Andrew F. Alexis, Melinda Gooderham, Shawn G. Kwatra, Ahmad Amin, Susan Taylor, Ramon Espaillat, Trisha Rettig, Tianshuang Wu, Linyu Shi, Mark I. Kaldas, Deanne M. Dilley, Ranjeeta Sinvhal, Chudy Nduaka, Benjamin Lockshin   +13 more
doaj   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Black and African American Connections to Parkinson's Disease Study: Addressing Missing Diversity in Parkinson's Disease Genetics. [PDF]

Mov Disord, 2022
Bandres-Ciga S, Black and African American Connections to Parkinson's Disease (BLAAC PD) Study Group.   +1 more
europepmc   +1 more source

Anatomists' experience and perspectives on the international transfer of human remains for the purpose of education

Anatomical Sciences Education, EarlyView.
Abstract Anecdotally, educational institutions without access to human remains may choose to import these from other countries; however, there is currently no published information illuminating the existence of this trade. This study therefore aimed to document the nature of international transfer of human remains for education, and explore anatomists'
Jackie Hazelhurst, Jon Cornwall, Brandi Schmitt, Brendon Billings, Susana Biasutto, Andreas Winkelmann, Jian Yang, Laura Johnson   +7 more
wiley   +1 more source

Perceived Benefits and Barriers of a COVID-19 Test to Stay Program in a School District Serving Black or African American People With Low Income, December 2021. [PDF]

Public Health Rep, 2023
Kamitani E, Holman EJ, Philpott D, Parasram VD, Ruth LJ, Onyeuku C, Carter B, Gwynn E, Beck TW, Regan K, Hagler LR, Clark A, Shelley G, Thomas ES.   +13 more
europepmc   +1 more source